161397-68-8 - Names and Identifiers
161397-68-8 - Physico-chemical Properties
Molecular Formula | C9H6ClNO
|
Molar Mass | 179.6 |
Density | 1.400±0.06 g/cm3(Predicted) |
Boling Point | 340.3±15.0 °C(Predicted) |
pKa | 15.74±0.30(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
161397-68-8 - Introduction
1H-Indole-5-carbonyl chloride (9CI)(also known as ketochlorindole) is an organic compound with the chemical formula C10H6ClNO. It has the following properties:
1. Appearance: 1H-Indole-5-carbonyl chloride (9CI) is a colorless to pale yellow crystal or powder substance.
2. Melting point and boiling point: its melting point is about 124-125 ℃, boiling point is about 335 ℃.
3. Solubility: It can be dissolved in organic solvents such as ether, ethanol and dichloromethane.
1H-Indole-5-carbonyl chloride (9CI) is mainly used:
1. As a reagent for Organic Synthesis: it can be used as an intermediate for the synthesis of organic compounds, especially indole derivatives.
2. As a luminescent material: Because of its luminescent properties, it can be used as a fluorescent probe, dye, etc. in the field of chemiluminescence and material science.
There are many ways to prepare 1H-Indole-5-carbonyl chloride (9CI), one of the common methods is as follows:
Reaction of 5-carbonyl-lh-indole with phosphorus chloride (PCl5) in dry dichloromethane, usually at low temperature. At the end of the reaction, the product is washed with dilute sulphuric acid, then neutralized with sodium carbonate solution and crystallized, finally obtaining a pure product.
Regarding safety information, there are few specific toxicity and hazard data for 1H-Indole-5-carbonyl chloride (9CI). However, as a chemical, it can be irritating to the skin, eyes and respiratory tract, so care should be taken when handling it, such as wearing appropriate protective gloves, glasses and masks. At the same time, avoid ingesting and inhaling its powder and avoid reacting with other chemicals. When using or handling this compound, follow proper laboratory practices to ensure safe use. It is best to read the safety data sheet (SDS) of the compound before handling for more detailed safety information.
Last Update:2024-04-10 22:29:15