N-Boc-N,N-bis(2-bromoethyl)amine is an organic compound with the chemical formula C11H18Br2N2O2. It is a white solid with low solubility. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: white solid
2. Molecular Weight: 327.08g/mol
3. Melting Point: 101-103 ° C
4. Solubility: insoluble in water at room temperature, soluble in some organic solvents such as dimethylformamide (DMF) and dichloromethane.
Use:
1. N-Boc-N,N-bis(2-bromoethyl)amine is a commonly used reagent that can be used in different reactions in organic synthesis.
2. It can be used as a coupling reagent to introduce amino protecting group (N-BOC) in organic synthesis.
3. N-Boc-N,N-bis(2-bromoethyl)amine is also used in the field of medicine and is used as a drug intermediate.
Method:
N-Boc-N, the preparation of N-bis(2-bromoethyl)amine is usually carried out by the following steps:
1. React N,N-bis(2-bromomethyl) amine with N-BOC acid to generate product N-Boc-N,N-bis(2-bromoethyl)amine.
Safety Information:
1. N-Boc-N,N-bis(2-bromoethyl)amine should comply with general laboratory safety procedures during use and storage.
2. It may be irritating to the eyes, skin and respiratory system, so it is necessary to wear appropriate protective equipment, such as gloves, glasses and protective clothing.
3. Avoid inhaling the dust of the compound or contacting the skin, and avoid ingesting food or drinking water.
4. When handling this compound, make sure to operate in a well-ventilated area.