15837-41-9 - Names and Identifiers
Name | 5-Hydroxy-1,4-dihydropyrimidin-4-one
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Synonyms | 5-Hydroxy-4(1H)-pyrimidinone 5-hydroxypyrimidin-4(1H)-one 5-hydroxypyrimidin-4(3H)-one 5-HydroxypyriMidin-4(3H)-one 4(1H)-PyriMidinone, 5-hydroxy- 4(1H)-Pyrimidinone, 5-hydroxy- (9CI) 5-Hydroxy-1,4-dihydropyrimidin-4-one 5-hydroxy-3,4-dihydropyriMidin-4-one 5-Hydroxy-1,4-dihydropyrimidin-4-one
5-Hydroxy-4(1H)-pyrimidinone
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CAS | 15837-41-9
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EINECS | 604-604-1 |
InChI | InChI=1/C4H4N2O2/c7-3-1-5-2-6-4(3)8/h1-2,7H,(H,5,6,8) |
15837-41-9 - Physico-chemical Properties
Molecular Formula | C4H4N2O2
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Molar Mass | 112.09 |
Density | 1.55±0.1 g/cm3(Predicted) |
Melting Point | 268-269 °C (decomp) |
Boling Point | 308.6°C at 760 mmHg |
Flash Point | 140.4°C |
Vapor Presure | 0.00037mmHg at 25°C |
pKa | 8.47±0.40(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.648 |
15837-41-9 - Introduction
5-Hydroxy-1,4-dihydropyrimidin-4-one, also known as 5-hydroxymethyl-4-pyrimidinone or 5-hydroxyluracil, is an organic compound. Its molecular formula is C5H6N2O2 and its molecular weight is 126.11g/mol.
Here are some of the properties and uses of 5-Hydroxy-1,4-dihydropyrimidin-4-one:
Nature:
1. Appearance: White or off-white crystalline solid.
2. Melting point: About 180-183 degrees Celsius.
3. Solubility: It is difficult to dissolve in water, but it is soluble in many organic solvents.
Use:
1. Cosmetics and personal care products: As an antioxidant and skin conditioner, it helps reduce the damage of free radicals to the skin.
2. Pharmaceutical field: used in the synthesis of certain drugs, such as Yangxin antipsychotics and high blood pressure drugs.
3. Food additives: as health care products and increase the quality of food additives.
Method:
There are many preparation methods for 5-Hydroxy-1,4-dihydropyrimidin-4-one, mainly including:
1. Reaction of urea and formic acid: Under alkaline conditions, urea and formic acid react to produce 5-Hydroxy-1,4-dihydropyrimidin-4-one.
2. Pyrimidine and glycolic acid reaction: under acidic conditions, pyrimidine and glycolic acid react to produce 5-Hydroxy-1,4-dihydropyrimidin-4-one acetate.
The preparation method can also be improved and adjusted according to specific needs.
Safety Information:
5-Hydroxy-1,4-dihydropyrimidin-4-one is a relatively safe compound, but the following safety precautions still need to be paid attention:
1. Avoid inhalation, ingestion or contact with skin and eyes.
2. If accidental contact occurs, immediately flush the affected area with plenty of water and seek medical help.
3. Please keep it properly and keep it away from fire and radiation.
When using or handling 5-Hydroxy-1,4-dihydropyrimidin-4-one, please be sure to follow appropriate safety procedures and operate in accordance with relevant regulations.
Last Update:2024-04-09 15:17:53