Name | 2-Chloro-3-(4-methyl-1-piperazinyl)quinoxaline |
Synonyms | VUF 10166 2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline 2-Chloro-3-(4-methylpiperazin-1-yl)quinoxaline 2-Chloro-3-(4-methyl-1-piperazinyl)quinoxaline 2-Chloro-3-(4-Methyl-1-piperazinyl)quinoxaline Quinoxaline, 2-chloro-3-(4-methyl-1-piperazinyl)- |
CAS | 155584-74-0 |
InChI | InChI=1S/C13H15ClN4/c1-17-6-8-18(9-7-17)13-12(14)15-10-4-2-3-5-11(10)16-13/h2-5H,6-9H2,1H3 |
Molecular Formula | C13H15ClN4 |
Molar Mass | 262.74 |
Density | 1.279±0.06 g/cm3(Predicted) |
Boling Point | 389.6±42.0 °C(Predicted) |
pKa | 6.55±0.42(Predicted) |
Storage Condition | -20℃ |
In vitro study | VUF10166 was less active at the 5-HT3AB receptor, with an Ki of 22 nM. VUF10166 may be used to distinguish between 5-HT3A and 5-HT3AB receptors. VUF10166 has no activity at the α7 nACh receptor. VUF10166 also acts as a partial agonist of the 5-HT3A receptor with an EC50 of 5.2 μM, indicating that VUF10166 is unlikely to bind to the receptor pore. |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.806 ml | 19.03 ml | 38.06 ml |
5 mM | 0.761 ml | 3.806 ml | 7.612 ml |
10 mM | 0.381 ml | 1.903 ml | 3.806 ml |
5 mM | 0.076 ml | 0.381 ml | 0.761 ml |