152167-85-6 - Names and Identifiers
152167-85-6 - Physico-chemical Properties
Molecular Formula | C9H5FN2O2
|
Molar Mass | 192.15 |
Density | 1.446±0.06 g/cm3(Predicted) |
Boling Point | 329.7±27.0 °C(Predicted) |
Flash Point | 153.2°C |
Vapor Presure | 0.000335mmHg at 25°C |
pKa | 0.22±0.29(Predicted) |
Refractive Index | 1.654 |
152167-85-6 - Introduction
5-Fluoro-8-Nitro Quinoline is an organic compound with the chemical formula C9H5FN2O2. The following is a description of the nature, use, preparation and safety information of 5-Fluoro-8-Nitro Quinoline:
1. Nature:
-Appearance: 5-Fluoro-8-Nitro Quinoline is a pale yellow crystal or powdery substance.
-Melting point: About 117-118 ° C.
-Solubility: Soluble in some organic solvents such as ethanol, methanol and dimethyl sulfoxide.
-Stability: Relatively stable under regular conditions, but avoid contact with strong oxidants, avoid high temperatures, fire sources and open flames.
2. Use:
- 5-Fluoro-8-Nitro Quinoline is an important organic synthesis intermediate, which can be used to synthesize a variety of organic compounds and functional materials.
-It is often used as a building block for organic heterocyclic compounds and can be used to prepare fluorescent dyes, photosensitive compounds, anti-cancer drugs, etc.
3. Preparation method:
The synthesis of-5-Fluoro-8-Nitro Quinoline can be achieved by a variety of methods. For example, 2-amino-6-fluoropyridine can be reacted with nitric acid to give 5-fluoro-8-nitroquinoline.
-In the preparation process, it is generally necessary to control the reaction conditions, such as reaction temperature, reaction time and the ratio of reactants.
4. Safety Information:
- 5-Fluoro-8-Nitro Quinoline is an organic compound, which has certain toxicity and irritation. Please maintain proper laboratory safety operations.
-Wear suitable personal protective equipment such as protective glasses, protective gloves and protective clothing when operating.
-Avoid contact with skin, eyes and mucous membranes, avoid inhalation of dust or gas, avoid ingestion.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.
Please note that due to the nature and use of chemicals that require expertise and laboratory equipment support, relevant experimental or industrial preparations should follow appropriate regulations and safe operating procedures.
Last Update:2024-04-09 15:17:52