Name | ditiocarb sodium |
Synonyms | NaDDTC ditiocarb sodium Sodium diethyldithiocarbamate Sodium Diethyl Dithiocarbamate sodium diethylcarbamodithioate sodium carbamodithioate - butane |
CAS | 148-18-5 |
EINECS | 205-710-6 |
InChI | InChI=1/C4H10.CH3NS2.Na/c1-3-4-2;2-1(3)4;/h3-4H2,1-2H3;(H3,2,3,4);/q;;+1/p-1 |
Molecular Formula | C5H10NNaS2 |
Molar Mass | 171.26 |
Density | 1.1000 |
Melting Point | 95℃ |
Boling Point | 176.4℃ at 760mmHg |
Water Solubility | >=10 g/100 mL at 14℃ |
Appearance | Form Liquid, Color Clear, colorless |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Physical and Chemical Properties | Chemical properties trihydrate: thin and irregular flake crystals obtained from acetone, melting point 94~102 ℃; The melting point is also reported to be 90~92 ℃. Easily soluble in water, soluble in ethanol, methanol or acetone, insoluble in ether or benzene. The aqueous solution is alkaline and slowly decomposes. UV maximum absorption (ethanol):257,290nm(ε1200,13000). Acute toxicity LD50 rats, mice (mg/kg):2830,1870 oral; Mice:>1000 intravenous injection. |
Use | The use of low molecular sulfide immune enhancer can promote the maturation of T cells, increase the total amount of T4 cells and improve the function of natural killer cells, and has a synergistic effect with zidovudine. For AIDS. |
UN IDs | 3077 |
Hazard Class | 9 |
Packing Group | III |
Reference Show more | 1. Liu Qiumei, Tian Weiwei, Yu Guangyi, et al. Pre-column Derivatization-HPLC Determination of Pharmacokinetic Parameters of Bucucurfan in Rabbits [J]. Modern Applied Pharmacy in China, 35(9). 2. [IF = 6.165] Yang Wang et al."Synthesis of Fe3O4 @ SiO2-PHEMA via redox of H2O2 and Fe2 for efficient removal of Cu2 from aqueous solution." J Mol Liq. 2019 Dec;296:111865 |
dissolve diethanolamine in methanol, add carbon disulfide methanol solution, drop 40% sodium hydroxide methanol solution, filter out the precipitated crystals, wash with methanol for 3-4 times, and then recrystallize with methanol, after drying, pure Sodium diethyldithiocarbamate was obtained.
rat, mouse oral LD50;2830mg/kg, 1870mg/kg; Mouse intravenous injection LD50: >lOOOmg/kg. Staff should be protected. If the eyes and skin are touched, they should be immediately rinsed with plenty of flowing water. The working environment should be well ventilated. Mixing with oxidant and edible chemicals is strictly prohibited.