Name | L(-)-Proline |
Synonyms | Proline H-Pro-OH L-Proline L(-)-Proline L(-)-Proline 0 L-PROLINE, NATURAL L-PROLINE, SYNTHETIC 2-Pyrrolidinecarboxylic acid L-(-)-PROLINE ((S)-(-)-PROLINE) (S)-Pyrrolidine-2-carboxylic acid L-Proline ,L-2-Pyrrolidinecarboxylic acid |
CAS | 147-85-3 |
EINECS | 205-702-2 |
InChI | InChI=1/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m1/s1 |
InChIKey | ONIBWKKTOPOVIA-UHFFFAOYSA-N |
Molecular Formula | C5H9NO2 |
Molar Mass | 115.13 |
Density | 1.35 |
Melting Point | 228 °C (dec.) (lit.) |
Boling Point | 215.41°C (rough estimate) |
Specific Rotation(α) | -85.5 º (c=4, H2O) |
Flash Point | 106.3°C |
JECFA Number | 1425 |
Water Solubility | soluble |
Solubility | Soluble in water and ethanol, insoluble in ether, butanol and isopropanol, soluble in inorganic acid. Solubility in water: 1623g/L (25°C), ethanol solubility: 67g/100mL (19°C). |
Vapor Presure | 0Pa at 25℃ |
Appearance | Crystallization |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.05', , 'λ: 280 nm Amax: 0.05'] |
Merck | 14,7780 |
BRN | 80810 |
pKa | 1.95, 10.64(at 25℃) |
PH | 6.0-7.0 (25℃, 1M in H2O) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Hygroscopic |
Refractive Index | -85 ° (C=4, H2O) |
MDL | MFCD00064318 |
Physical and Chemical Properties | density 1.35 |
Use | Used for amino acid injection, compound amino acid infusion, food additives, nutrition supplement |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
WGK Germany | 3 |
RTECS | TW3584000 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Yes |
HS Code | 29339990 |
Toxicity | LD50 orally in Rabbit: > 5110 mg/kg |
Raw Materials | Dextrose Anhydrate |
Downstream Products | D-Proline captopril lisinopril Enalapril |
amino acid drugs. It is one of the raw materials for compound amino acid infusion. Protein Supplementation for malnutrition, protein deficiency, severe gastrointestinal disorders, Burns and after surgery.
sealed storage.