142702-31-6 - Names and Identifiers
142702-31-6 - Physico-chemical Properties
Molecular Formula | C10H11NNa2O12S4
|
Molar Mass | 511.43338 |
Melting Point | >222°C (dec.) |
Solubility | Water (Slightly) |
Appearance | Solid |
Color | Off-White |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Stability | Moisture and Temperature Sensitive |
142702-31-6 - Introduction
3,3 "-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester Disodium Salt(3,3"-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester Disodium Salt) is a reagent for chemical cross-linking of proteins. Its nature is as follows:
1. Chemical properties: DTSSP is a bifunctional crosslinking reagent containing disulfide bonds and has two active groups. It is a white to pale yellow solid that dissolves easily in water.
2. Uses: DTSSP is mainly used for immobilizing chemically cross-linked proteins, and has applications in the study of protein complex structure, subcellular localization, and protein interactions. By introducing disulfide bonds, DTSSP can stabilize the interaction between proteins and help to study the structure and function of proteins.
3. preparation method: DTSSP is generally prepared by reacting 3,3 "-bis (2-bromoethyl) dithiopental thiophene with sodium N-hydroxysuccinimidamide in an organic solvent. The specific preparation method may vary according to different literatures.
4. Safety Information: When using DTSSP, attention should be paid to its toxicity and irritation. It may be irritating to the eyes and skin, so wear protective glasses and gloves when operating. At the same time, it should be stored in a dry, cool place to avoid contact with oxygen, moisture and strong oxidants.
Last Update:2024-04-09 21:11:58