1369017-00-4 - Names and Identifiers
1369017-00-4 - Physico-chemical Properties
Molecular Formula | C10H10ClN3O
|
Molar Mass | 223.66 |
Density | 1.299±0.06 g/cm3(Predicted) |
Boling Point | 370.5±52.0 °C(Predicted) |
pKa | 6.13±0.29(Predicted) |
1369017-00-4 - Introduction
3-(4-Chloro-2-methylphenyl)-1,2, 4-oxadiazole-5-methylamine is an organic compound with the chemical formula C10H8ClN3O and a molecular weight of 221.64g/mol.
In terms of properties, it is a yellow to orange solid, soluble in some organic solvents such as methanol and dimethyl sulfoxide. It is stable at room temperature and relatively stable under dry conditions.
This compound is often used as a pharmaceutical intermediate, especially in the synthesis of anti-cancer drugs. It can be used as a raw material for anti-tumor drugs such as oxazole deoxynucleoside drugs and cyclosporine drugs. In addition, it can also be used as a synthetic intermediate of antibacterial drugs, which has important application value in drug research and development and chemical synthesis.
3-(4-chloro-2-methylphenyl)-1,2, 4-oxadiazole-5-methylamine can be prepared by the oxidation reaction of acetylene glycol. A common preparation method is to react 4-chloro-2-methylbenzamide with ethyl acetoacetate, then chlorinate the resulting product, and finally react with ammonium hypochlorite in isopropanol to obtain the desired product.
Regarding safety information, it is an organic compound, and safety measures should be paid attention to when using it, such as wearing chemical protective gloves, safety glasses and protective clothing. In addition, it should be kept away from fire and oxidizing agents and stored in a cool, dry place.
Last Update:2024-04-10 22:30:50