132287-55-9 - Names and Identifiers
132287-55-9 - Physico-chemical Properties
Molecular Formula | C24H21ClN2
|
Molar Mass | 372.89 |
Density | 1.11 |
Boling Point | 516.0±45.0 °C(Predicted) |
pKa | 6.09±0.61(Predicted) |
132287-55-9 - Introduction
4-(2-Chloroethyl)-1-tritylimidazole (abbreviated CEMZ) is an organic compound whose chemical formula is C22H17ClN2. The following is a description of the nature, use, preparation and safety information of CEMZ:
Properties: CEMZ is a white crystalline solid with good stability at room temperature. It is soluble in a variety of organic solvents (such as alcohol, ether, ether, etc.), but insoluble in water.
Purpose: CEMZ is a commonly used imidazole compound, which is often used as a catalyst or ligand in organic synthesis reactions. It has high chemical reaction activity and good catalytic effect for some organic reactions. In addition, CEMZ can also be used in organic metal chemical reactions, reagent synthesis and pharmaceutical fields.
Preparation method: There are many synthesis methods for CEMZ. One of the common methods is to react terephthalic acid and phenylacetylene under alkaline conditions to obtain 2-[1-(phenyl)-2-phenylethyl] benzoic acid. Then, 2-[1-(phenyl)-2-phenylethyl] benzoic acid is reacted with chloroethanol to obtain 4-(2-chloroethyl)-1-tribenzylimidazole through condensation.
Safety information: CEMZ has good safety under normal use conditions, but the following safety precautions should be paid attention to: avoid prolonged skin contact and avoid inhaling its dust or gas. Personal protective equipment, such as laboratory gloves and safety glasses, should be worn during use. In case of accidental contact or inhalation, rinse immediately with plenty of water and seek medical help if necessary. Proper storage and handling of CEMZ can avoid potential hazards.
Last Update:2024-04-09 15:17:51