113893-02-0 - Names and Identifiers
113893-02-0 - Physico-chemical Properties
Molecular Formula | C9H9BrN2O
|
Molar Mass | 241.08 |
Density | 1.50±0.1 g/cm3(Predicted) |
Melting Point | 95-98 °C(Solv: ethyl ether (60-29-7); hexane (110-54-3)) |
Boling Point | 316.8±37.0 °C(Predicted) |
Flash Point | 145.4°C |
Vapor Presure | 0.000401mmHg at 25°C |
pKa | -1.04±0.28(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Sensitive | IRRITANT |
Refractive Index | 1.567 |
MDL | MFCD03787138 |
113893-02-0 - Introduction
5-Bromo-2-methoxy-4, 6-dimethylnicotinonitrile (5-bromo-2-methoxy-4,6-dimethylpyrimidine) is an organic compound. Its formula is C8H10BrN2O.
Nature:
1. Appearance: 5-bromo-2-methoxy-4, 6-dimethylnicotinonitrile is a white crystalline solid.
2. Melting point: about 69-73°C.
3. Boiling point: about 271-273°C.
4. solubility: can be dissolved in organic solvents such as methanol, ethanol and dimethyl sulfoxide, insoluble in water.
Use:
5-Bromo-2-methoxy-4, 6-dimethylnicotinonitrile has a wide range of applications in organic synthesis, mainly for the preparation of pesticides, pharmaceuticals and other organic compounds. It can be used as an intermediate of a variety of glyphosate pesticides, and can also be used to synthesize biologically active compounds.
Method:
The preparation of 5-bromo-2-methoxy-4, 6-dimethylnicotinonitrile can be carried out by the following methods:
1.2-methoxy -4,6-dimethyl nicotinonitrile and hydrogen bromide are reacted to obtain the product.
2. Alternatively, 2-methyl -4, 6-dimethylnicotinonitrile can be reacted with methyl bromide to obtain the product.
Safety Information:
When treating 5-bromo-2-methoxy-4, 6-dimethylnicotinonitrile, the following items should be paid attention:
1.5-Bromo-2-methoxy-4, 6-dimethylnicotinonitrile may be irritating to eyes and skin, please avoid direct contact.
2. appropriate protective gloves, masks and goggles should be worn during use.
3. in the operation should be carried out in the case of good ventilation.
4. if accidental contact or misuse, please seek medical treatment in time.
Last Update:2024-04-09 19:05:45