112725-89-0 - Names and Identifiers
Name | 3,5-Diaminosalicylic acid
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Synonyms | 3,5-Diaminosalicylic Mesalamine EP Impurity J Mesalazine EP Impurity J 3,5-Diaminosalicylic acid 3,5-diamino-2-hydroxybenzoic acid 3,5-diaMino-2-hydroxybenzoic acid Benzoic acid, 3,5-diaMino-2-hydroxy- 3,5-Diaminosalicylic Acid Reference Standard
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CAS | 112725-89-0
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InChI | InChI=1/C7H8N2O3/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2,10H,8-9H2,(H,11,12) |
112725-89-0 - Physico-chemical Properties
Molecular Formula | C7H8N2O3
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Molar Mass | 168.15 |
Density | 1.602±0.06 g/cm3(Predicted) |
Boling Point | 455.8±45.0 °C(Predicted) |
Flash Point | 229.4°C |
Vapor Presure | 4.24E-09mmHg at 25°C |
pKa | 0.96±0.14(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Refractive Index | 1.768 |
112725-89-0 - Reference
Reference Show more | 1. Jiang Qianqian, Gao Na, Tian Yaoqi, et al. Study on the effect of new heating treatment on the properties of wheat starch [J]. Food Research and Development, 2019(11).
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112725-89-0 - Introduction
3,5-Diaminosalicylic acid, also known as 3,5-diaminosalicylic acid hydrate or 3,5-diaminosalicylate, is an organic compound. The following is a description of the properties, uses, preparation and safety information of 3,5-diaminosalicylic acid:
Nature:
-Chemical formula: C7H9NO3
-Molecular weight: 155.16g/mol
-Appearance: White to light yellow crystal or powder
-Solubility: Dissolved in water and alcohol, insoluble in non-polar solvents
Use:
-PHARMACEUTICAL: 3,5-Diaminosalicylic acid is an over-the-counter pain reliever commonly used to relieve headaches, joint pain and muscle pain. It also has anti-inflammatory and antipyretic effects and is sometimes used to treat fever and cold symptoms.
-Cosmetics field: Due to its anti-inflammatory and moisturizing properties, 3,5-diaminosalicylic acid is often added to certain skin care products and cosmetics to treat acne and reduce inflammation.
Preparation Method:
The preparation method of 3,5-diaminosalicylic acid is relatively simple and can be carried out through the following steps:
1. salicylic acid (2-hydroxybenzoic acid) reacts with ammonia to generate hydrated salicylic acid.
2. the hydrated salicylic acid reacts with excess ammonia again to generate 3,5-diaminosalicylic acid.
Safety Information:
- 3,5-diaminosalicylic acid is irritating to the skin and eyes and should be rinsed with water immediately after contact.
-When using 3,5-diaminosalicylic acid drugs, pay attention to the dosage and medication time to avoid adverse reactions.
-Pregnant women, lactating women and children should consult a doctor before use.
- 3,5-Diaminosalicylic acid should not be used with other drugs, especially with salicylic acid and its derivatives, to prevent drug interactions.
Last Update:2024-04-09 02:00:41