111048-64-7 - Names and Identifiers
111048-64-7 - Physico-chemical Properties
Molecular Formula | C8H8N2O2S
|
Molar Mass | 196.23 |
Density | 1.500±0.06 g/cm3(Predicted) |
Boling Point | 474.8±37.0 °C(Predicted) |
pKa | 10.32±0.30(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
111048-64-7 - Introduction
1H-indole-7-sulfonamide is an organic compound, also known as 7-sulfonylindole. Its chemical formula is C9H8N2O3S and its molecular weight is 220.24g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
1H-Indole -7-sulfonamide is a white crystalline powder with a bitter taste. It is soluble in acid and alkali at room temperature, slightly soluble in water, and easily soluble in most organic solvents.
Use:
1H-indole-7-sulfonamide is commonly used as a reagent and intermediate in organic synthesis. It can be used to synthesize compounds with pharmaceutical activity, such as indole drugs, antibiotics, etc. In addition, it can also be used as a catalyst in organic synthesis, an enzyme inhibitor, etc.
Preparation Method:
There are many methods for the synthesis of 1H-indole-7-sulfonamide, one of which is commonly used by nucleophilic substitution reaction. This procedure generally involves reacting an indole with a nucleophile, such as a sulfonyl chloride, under basic conditions to produce the desired product.
Safety Information:
The safety of 1H-indole-7-sulfonamide is generally high, but as an organic compound, it is still necessary to pay attention to safe operation. It is toxic and may cause irritation and allergic reactions when inhaled or in contact with the skin. During use, it is recommended to wear appropriate personal protective equipment, such as gloves, lab clothes and protective glasses. At the same time, it should be operated in a well-ventilated place and avoid contact with oxidants or strong bases. In storage and handling, should be properly kept, away from fire and flammable materials. In the event of an accident, seek professional help immediately.
Last Update:2024-04-09 21:11:58