Name | 2-Picoline |
Synonyms | NSC-3409 Picoline HSDB 5819 2-Picoline Methylpyridine 2-Methylpyidine α-Methylpyridine 2-Methylpyridine Pyridine, methyl- Pyridine, Reagent 2-picoline (alpha) 2-methylpyridine(2-Picoline) 2-Picoline (2-Methylpyridine) 2-Methylpyridine-d7(2-Picoline) |
CAS | 109-06-8 1333-41-1 |
EINECS | 203-643-7 |
InChI | InChI=1/C6H7N/c1-6-4-2-3-5-7-6/h2-5H,1H3 |
InChIKey | BSKHPKMHTQYZBB-UHFFFAOYSA-N |
Molecular Formula | C6H7N |
Molar Mass | 93.13 |
Density | 0.942-0.946 at 20 °C0.943 g/mL at 25 °C (lit.) |
Melting Point | -70 °C (lit.) |
Boling Point | 128-129 °C (lit.) |
Flash Point | 79°F |
Water Solubility | MISCIBLE |
Solubility | H2O: freely soluble |
Vapor Presure | 10 mm Hg ( 24.4 °C) |
Vapor Density | 3.2 (vs air) |
Appearance | Liquid |
Color | Clear pale yellow |
Odor | Unpleasant |
Merck | 14,7400 |
BRN | 104581 |
pKa | 5.97(at 20℃) |
PH | 8.5 (100g/l, H2O, 20℃) |
Storage Condition | Store below +30°C. |
Stability | Stable. Flammable. Incompatible with strong oxidizing agents, sulfuric acid, acids, metals, iron (II) sulfate, hydrogen peroxide. Hygroscopic. |
Sensitive | Hygroscopic |
Explosive Limit | 1.4-8.6%(V) |
Refractive Index | n20/D 1.500(lit.) |
Physical and Chemical Properties | Trait a colorless oily liquid with a strong unpleasant pyridine odor. melting point -64 ℃ boiling point 129.5 ℃ relative density 0.9462 refractive index 1.4957 flash point 38.9 ℃ soluble in acetone and ether. Miscible with water and ethanol. |
Use | It is used as a raw material for the synthesis of medicines, dyes and resins, and can be used to prepare fertilizer synergists, herbicides, livestock repellents, rubber accelerators, dye intermediates, etc. |
Risk Codes | R10 - Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37 - Irritating to eyes and respiratory system. R24 - Toxic in contact with skin R20/22 - Harmful by inhalation and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
UN IDs | UN 2313 3/PG 3 |
WGK Germany | 1 |
RTECS | TJ4900000 |
TSCA | Yes |
HS Code | 29333999 |
Hazard Class | 3 |
Packing Group | III |
Toxicity | LD50 orally in rats: 1.41 g/kg (Smyth) |
Raw Materials | Benzene Ammonia Sulfuric acid |
Downstream Products | Bisacodyl chlorphenamine hydrogen maleate 2-Pyridinealdoxime methochloride |
natural oily liquid with the odor of pyridine. Spontaneous ignition point 537.8. Soluble in water, can be miscible with alcohol, ether. In case of open flame, high heat or contact with oxidant, there is a risk of combustion explosion. Toxic nitrogen oxide smoke is released by thermal decomposition. In case of high fever, the internal pressure of the container increases, and there is a risk of cracking and explosion.
The crude pyridine separated from coal tar is subjected to atmospheric distillation in a packed column, and the water in the pyridine is removed by azeotropic distillation of pure benzene and water, that is, 2 A methyl pyridine product. Alternatively, it is obtained by the reaction of an aldehyde with ammonia gas or by the catalytic reaction of acetylene and ammonia.
corrosion inhibitors for hydrochloric acid and other industrial pickling in acidizing and fracturing processes of oil and gas wells.
rat oral LD50:1.41g/kg. Store in a cool, ventilated warehouse. Keep away from fire and heat source. The bin temperature should not exceed 30 ℃. Protection from direct sunlight. Keep the container sealed. Should be stored separately from the oxidant.