Name | Taurine |
Synonyms | TATU TURIN TAURINE Taurine 2-sulfoethylamine TAURINE extrapure CHR Aminoethanesulfonic acid 2-amino-ethanesulfonicaci 2-Aminoethanesulfonic acid 2-Aminoethanesulphonic acid 5-Ferrocenyl valeric acid esters N~4~-(6-methoxyquinolin-8-yl)pentane-1,4-diamine |
CAS | 107-35-7 |
EINECS | 203-483-8 |
InChI | InChI=1/C2H7NO3S/c3-1-2-7(4,5)6/h1-3H2,(H-,4,5,6) |
InChIKey | XOAAWQZATWQOTB-UHFFFAOYSA-N |
Molecular Formula | C2H7NO3S |
Molar Mass | 125.15 |
Density | 1.00g/mLat 20°C |
Melting Point | >300 °C (lit.) |
JECFA Number | 1435 |
Water Solubility | 5-10 g/100 mL at 23.5 ºC |
Solubility | Soluble in water, insoluble in ethanol, ether and acetone. |
Appearance | White crystal or crystalline powder |
Color | White |
Maximum wavelength(λmax) | ['λ: 260 nm Amax: 0.006', , 'λ: 280 nm Amax: 0.005'] |
Merck | 14,9074 |
BRN | 1751215 |
pKa | 1.5(at 25℃) |
PH | 4.5-6.0 (25℃, 0.5M in H2O) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Sensitive | Easily absorbing moisture |
Refractive Index | 1.5130 (estimate) |
MDL | MFCD00008197 |
Physical and Chemical Properties | melting point 300°C |
Use | Used as a Biochemical reagent |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 2 |
RTECS | WX0175000 |
TSCA | Yes |
HS Code | 29211980 |
Toxicity | LD50 orally in Rabbit: > 5000 mg/kg |
Raw Materials | Sulfuric acid Sodium sulfite Ethanolamine |
Reference Show more | 1. Li Ya, Liu Qi, Zhang Juanjuan, et al. Effects of Different Pretreatment Methods on Nutritional Components of Oyster Peptide [J]. Journal of Food Safety and Quality Inspection 2018(13). 2. Cheng Ming and Wang Wei Chen Weixing Zhang Xiaojie Wang Xinxia. Preparation of Chewable Tablets and Its Anti-fatigue Effect on Mice [J]. Journal of the Second Military Medical University 2017 38(06):799-803. 3. Ma Guizhi, Chen Xueshan, Jiang Sisi, Duan Xia. Determination of 16 Amino Acids in Urine of Rheumatoid Arthritis Rats by Pre-column Derivative HPLC-UV [J]. Journal of Xinjiang Medical University, 2018,41(08):1001-1005. 4. Xie Dongqi, Liu Qi, Su Zezhi, et al. Effect of taurine and antibiotic compound on preservation effect of pig semen at room temperature [J]. Journal of Northwest Agriculture, 2017, 26(006):820-826. 5. Li Sisi, Cao Shaoqian, Meng Ke, etc. Flavor Changes of Fish Meal Processing Squeeze after Enzymatic Fermentation [J]. Journal of Nuclear Agriculture, 2020, v.34(04):96-104. 6. Yan Chao, Hou Lijuan, Qi Xiaoru, et al. Analysis of Changes of Amino Acids and Organic Acids in Fermentation of Red Jujube Brandy [J]. Food Industry Science and Technology, 2017, 38(014):121-125. 7. Marina Cullman, bao Yihong. Screening and identification of cholesterol-lowering strains derived from traditional enzymes and analysis of bile salt hydrolase activity [J]. Chinese Food Journal, 2021,21(01):266-275. 8. Li Sisi, Chu Yingyan, Yin Xiaoqing, Liu Liang, Cao Shaoqian, Ma Danni, Qi Xiangyang. Technology and Quality Analysis of Fish Juice Preparation from Fish Meal Processing Squeeze [J]. Chinese food journal, 2020,20(10):160-168. 9. [IF = 3.497] C.-X. Sun et al."Different preference is modulated by the feeding stimulants supplementation in different Chinese soft-shelled (Pelodiscus sinensis) basic diets." Aquacult Nutr.2018 FEb; 24(1):195-203 10. [IF = 6.057] Xinyue Li et al."Comprehensive evaluation integrating omics strategy and machine learning algorithms for consistency of calculus bovis from different sources." Talanta. 2022 Jan;237:122873 11. [IF = 4.466] Yao Tan et al."Multiomics Integrative Analysis for Discovering the Potential Mechanism of Dioscin against Hyperuricemia Mice." J Proteome Res. 2021;20(1):645-660 12. [IF = 4.36] Bao Yang et al."UPLC/Q-TOF-MS/MS-based metabolomics revealed the lipid-lowering effect of Ilicis Rotundae Cortex on high-fat diet induced hyperlipidemia." J Ethnopharmacol. 2020 Jun;256:112784 |
It can be obtained by hydrolyzing bovine bile or by extracting and concentrating fish and shellfish such as cuttlefish, and meat and viscera of mammals. It can also be extracted from bezoar or synthesized chemically.
This product is 2-aminoethanesulfonic acid. Calculated on a dry basis, containing no less than 98.5% taurine (C2H7N03S).
taurine is a special kind of amino acid, which is essential for human growth and development. To promote the growth and development of children, especially infants and young children's brain and other important organs have a good effect. China's provisions can be used for children's oral liquid, the maximum dosage of 4.0~8.Og/kg; In infant food, dairy products and cereal products in the use of 0. 3~0. 5g/kg; In drink and milk drinks in the use of 0. 1~0. 5g/kg.
This product is packed with two-layer polyethylene bags lined with 25kg cardboard drum, carton or paper bag. Light-shielding, closed, in the dry place control at room temperature storage.
take 0. 5g of this product, add water 20mr to dissolve, according to UV-visible spectrophotometry (General rule 0401), determine the transmittance at 430mn wavelength, not less than 95.0%.
take this product 1. 0g, add water to make 50ml, take 25ml, check according to law (General rule 0801), and standard sodium chloride solution 5. 0ml of the control solution should not be more concentrated (0.01%).
Take 2. 0g of this product and check it according to law (General rule 0802). Compared with the control solution made of 2. 0ml of standard potassium sulfate solution, it should not be more concentrated (0. 01%).
take 0.10g of this product and check it according to law (General rule 0808). Compared with the control solution made of 0.02% of standard ammonium chloride solution, it shall not be deeper ().
take an appropriate amount of this product, add water to dissolve and dilute to make a solution containing about 20mg per lml as a test solution; Take 1ml for precision measurement and put it in a 500ml measuring flask, dilute to the scale with water, shake, as a control solution; Take appropriate amount of taurine control and alanine control, add water to dissolve and dilute to make solution containing about 2mg per 1ml, take appropriate amount of each, equal volume mixing, shake, as the system applicable solution. According to the thin layer chromatography (General rule 0502) test, Draw 5 u1 of each of the above three solutions, and put them on the same silica gel G thin layer plate in the pattern of band-like spotting, with a band width of 5mm, with water-absolute ethanol-n-butanol-glacial acetic acid (150:150:100:1) as the developing solvent, expand, dry, spray with ninhydrin acetone solution (1-50), heat at 105°C for about 5 minutes until spots appear and immediately examined. The control solution should show a clear spot, and the system applicable solution should show two completely separated spots. Test solution such as impurity spots, not more than 1. The color should not be darker (0.2%) in comparison with the main spot of the control solution.
take this product and dry it at 105°C for 4 hours, and the weight loss shall not exceed 0.4% (General rule 0831).
take l.Og of this product and check it according to law (General rule 0841). The residue left shall not exceed 0.1%.
take l.Og of this product and check it according to law (General rule 0807). Compared with the control solution made of 0.001% of standard iron solution, it should not be more concentrated ().
The residue left under the item of taking the ignition residue shall not contain more than 10 parts per million of heavy metal when examined by law (General Principles 0821, Law II).
take l.Og of this product, add 23ml of water to dissolve, add 5ml of hydrochloric acid, check according to law (General rule 0822 first law), should comply with the provisions (0.0002%).
pharmaceutical excipients, solubilizers, etc.
take about 0.2g of this product, precision weighing, add water 50ml to dissolve, precision add neutral formaldehyde solution (take formaldehyde solution, add 5 drops of phenol song indicator, use 0.1 mol/L sodium hydroxide solution was adjusted to solution microscopic pink) 5ml, according to the potentiometric titration method (General 0701), with sodium hydroxide titration solution (0.lmol/L) titration. Each 1 ml of sodium hydroxide titration solution (0.1 mol/L) corresponds to 12.52mg of C2H7NO3S.
antipyretic analgesic.
light shielding, sealed storage.
This product contains taurine (C2H7N03S) should be 95.0% to 105.0% of the label amount.
This product is white or off-white.
take an appropriate amount of fine powder of this product (about 0.5g equivalent to taurine), add 10ml of water, shake to dissolve, and filter. 2ml of the filtrate was taken to adjust the p H value to neutral. 1ml of ninhydrin solution was added and heated in a water bath.
should be in accordance with the relevant provisions under The tablet item (General rule 0101).
Take 10 tablets of this product, precise weighing, fine grinding, precise weighing appropriate amount (about 0.2g equivalent to taurine), add water 25ml, shake to dissolve the main component, with sodium hydroxide titration solution (0.lmol/L) adjust the pH value to 7.0, add 15ml of formaldehyde solution whose pH value is adjusted to 9.0 in advance, shake well, and then use sodium hydroxide titration solution (0.1 mol/L) titrated to pH 9.0 for 30 seconds with sodium hydroxide titrant (0. The amount (ml) of 1 mol/L) was calculated. Each 1 ml of sodium hydroxide titration solution (0.1 mol/L) corresponds to 12.52mg of C2H7NO3S.
Same as taurine.
0.4g
light-shielded, sealed, and stored in a dry place.
This product contains taurine (C2H7N03S) should be 90.0% to 110.0% of the label amount.
The content of this product is white or white crystalline powder.
take an appropriate amount of the content of this product (equivalent to 0.5g of taurine), add 10ml of water to dissolve, filter, take 2ml of filtrate, adjust the pH value to neutral, add 1ml of ninhydrin test solution, when heated in a water bath, the solution appeared blue-purple.
should comply with the relevant provisions under the capsule (General rule 0103).
take the contents under the difference of loading amount, mix evenly, weigh an appropriate amount (about 0.2g equivalent to taurine) accurately, add 25ml of water, shake to dissolve, with sodium hydroxide titration solution (0.lmol/L) adjust the pH value to 7.0, add 15ml of formaldehyde solution whose pH value is adjusted to 9.0 in advance, shake well, and then use sodium hydroxide titration solution (0.1 mol/L) titrated to pH 9.0 for 30 seconds with sodium hydroxide titrant (0. The amount (ml) of 1 mol/L) was calculated. Each 1 ml of sodium hydroxide titration solution (0.1 mol/L) corresponds to 12.52mg of C2H7N03S.
Same as taurine.
(1)0.4g (2)0.5g
light-shielded, sealed, and stored in a dry place.
This product contains taurine (C2H7N03S) should be 90.0% to 110.0% of the label amount.
This product is white or off-white crystal or crystalline powder.
take an appropriate amount of fine powder of this product (equivalent to 0.5g of taurine), add 10ml of water, shake to dissolve, filter, take 2ml of filtrate, adjust the pH value to neutral, add 1ml of ninhydrin test solution, when heated in a water bath, the solution appeared blue-purple.
should comply with the relevant provisions under the paragraph of powder (General 0115).
take the contents under the difference of loading amount, mix evenly, weigh an appropriate amount (about 0.2g equivalent to taurine) accurately, add 25ml of water, shake to dissolve the main component, with sodium hydroxide titration solution (0.lmol/L) adjust the pH value to 7.0, add 15ml of formaldehyde solution whose pH value is adjusted to 9.0 in advance, shake well, and then use sodium hydroxide titration solution (0.1 mol/L) titrated to pH 9.0 for 30 seconds with sodium hydroxide titrant (O. The amount (ml) of 1 mol/L) was calculated. Each 1 ml of sodium hydroxide titration solution (0.1 mol/L) corresponds to 12.52 mg of C2H7N03S.
Same as taurine.
0.4g
It was kept in a dry place and closed.
This product contains taurine (C2H7N03S) should be 90.0% to 110.0% of the label amount.
This product is soluble granules.
should be consistent with the granules under the relevant provisions (General Principles 0104).
Same as taurine.
(1)0.4g (2)0.8g (3)1.2g
light-shielded, sealed, and stored in a dry place.
This product is colorless or almost colorless clear liquid.
Same as taurine.
( l)8ml:0.4g (2)10ml:0.5g
light shielding, closed storage.