Name | Ethylenediamine |
Synonyms | EDA amerstat274 Ethylenediamine Ethylendiaminum 1,2-Diaminoethane ethane-1,2-diamine ethane-1,1-diamine 1,2-ethylenediamine beta-Aminoethylamine EDA EthylenediaMine a (E)-ethene-1,2-diamine Ethylenediamineanhydrous Ethylenediamine diacetate 1,2-Diaminoethane anhydrous ETHYLENEDIAMINE FOR SYNTHESIS Ethylenediamine and derivatives |
CAS | 107-15-3 |
EINECS | 203-468-6 |
InChI | InChI=1/C2H8N2/c3-1-2-4/h1-4H2 |
InChIKey | PIICEJLVQHRZGT-UHFFFAOYSA-N |
Molecular Formula | C2H8N2 |
Molar Mass | 60.1 |
Density | 0.899 g/mL at 25 °C (lit.) |
Melting Point | 8.5 °C (lit.) |
Boling Point | 118 °C (lit.) |
Flash Point | 93°F |
Water Solubility | miscible |
Solubility | ethanol: soluble(lit.) |
Vapor Presure | 10 mm Hg ( 20 °C) |
Vapor Density | 2.07 (vs air) |
Appearance | Liquid, Fuming In Air |
Specific Gravity | 0.899 |
Color | colorless to pale yellow |
Odor | Strong ammoniacal odor; ammonia-like mild and ammoniacal odor. |
Exposure Limit | TLV-TWA 10 ppm (~25 mg/m3) (ACGIH,MSHA, and OSHA); IDLH 2000 ppm(NIOSH). |
Merck | 14,3795 |
BRN | 605263 |
pKa | 10.712(at 0℃) |
PH | 12.2 (100g/l, H2O, 20℃) |
Storage Condition | Flammables area |
Sensitive | Air Sensitive |
Explosive Limit | 2-17%(V) |
Refractive Index | n20/D 1.4565(lit.) |
Physical and Chemical Properties | Density 0.898 melting point 11°C boiling point 117-118°C refractive index 1.4555-1.4575 flash point 34°C water-soluble miscible |
Use | For the treatment of psoriasis, Malignant lymphoma, head and neck cancer, soft tissue sarcoma also has a certain role in the relief |
Hazard Symbols | C - Corrosive |
Risk Codes | R10 - Flammable R21/22 - Harmful in contact with skin and if swallowed. R34 - Causes burns R42/43 - May cause sensitization by inhalation and skin contact. |
Safety Description | S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 1604 8/PG 2 |
WGK Germany | 2 |
RTECS | KH8575000 |
FLUKA BRAND F CODES | 10-34 |
TSCA | Yes |
HS Code | 29212110 |
Hazard Class | 8 |
Packing Group | II |
Toxicity | LD50 orally in rats: 1.16 g/kg (Smyth) |
colorless and strongly alkaline volatile viscous liquid. Ammonia odor. Flammable. Soluble in water and ethanol, soluble in water hydrate formation. Slightly soluble in ether, insoluble in benzene. Ethylenediamine has strong alkaline, easy to salt when acid. It can absorb the moisture and carbon dioxide in the air to produce non volatile carbonate. Ethylenediamine can also form complexes with many inorganic substances. In case of open flame, high heat or contact with oxidant, there is a risk of combustion explosion. With sulfuric acid, nitric acid, hydrochloric acid and other strong acid reaction.
aqueous ammonia was added to dichloroethane and the mixture was heated to 115-120 °c for reaction. The reaction solution was evaporated until crystallization started, filtered, and washed with ethanol. Anhydrous ethylenediamine was obtained by distillation in a nitrogen bath.
for non-aqueous solution titration. Aminocarboxylic complexing agent. Determination of antimony, bismuth, cadmium, cobalt, copper, mercury, silver and uranium. Used as a curing agent for epoxy resin, protein, fibrin solvent.
rat oral LD50:1.16g/kg. This substance may be harmful to the environment, and special attention should be paid to the water body. Should be stored separately from oxidants and acids. Staff should be protected. If the eyes and skin are touched, they should be immediately rinsed with plenty of flowing water. Store in a cool, ventilated warehouse. Keep away from fire and heat source. Protection from direct sunlight.