L-2-chlorophenalaninol is an organic compound with the formula C9H12ClNO and a molecular weight of 185.65g/mol. The following is a description of its nature, use, preparation and safety information:
Nature:
L-2-Chlorophenylalaninol is a white crystalline powder with low solubility (soluble in water, ethanol and ether). Its melting point is about 146-151 degrees Celsius.
Use:
L-2-chlorophenylalaninol is a chiral compound, which is commonly used in chiral synthesis reactions in drug synthesis. It is a derivative of a natural beta-adrenoceptor blocker and can be used in the preparation of specific beta-adrenoceptor blocker drugs for neuroscience research. In addition, it can be used for chiral esterification and other chiral reactions in organic synthesis.
Preparation Method:
the preparation method of L-2-chlorophenylalaninol mainly includes the following steps: firstly, after hydrochloric acid treatment, alaninol and hydrochloric acid are condensed to obtain chloropropyl amino compound, then the compound reacts with p-nitrobenzene to generate p-nitrochloropropyl amino compound, and finally L-2-chlorophenylalaninol product is obtained through reduction reaction.
Safety Information:
L-2-chlorophenylalaninol needs to be safe during use and storage. It can be irritating and corrosive to the skin and eyes, so appropriate protective equipment must be worn. In addition, it may also have effects on the central nervous system, which requires avoidance of inhalation and prolonged exposure. When using, please follow the correct operating procedures and ensure proper ventilation conditions. If necessary, the compound should be used under the guidance of a chemical laboratory or experienced personnel.