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1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate

N-Boc-trans-4-fluoro-L-proline methyl ester

CAS: 203866-18-6

Molecular Formula: C11H18FNO4

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1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate - Names and Identifiers

Name N-Boc-trans-4-fluoro-L-proline methyl ester
Synonyms BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
(4R)-1-BOC-4-FLUORO-L-PROLINE METHYL ESTER
N-Boc-trans-4-fluoro-L-proline methyl ester
N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER
(2S,4R)-N-Boc-trans-4-fluoro-L-proline methyl ester
METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE
1-tert-Butyl 2-methyl (2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylate
1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
(2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylic acid O1-tert-butyl ester O2-methyl ester
1,2-pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
CAS 203866-18-6
InChI InChI=1/C11H18FNO4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6H2,1-4H3/t7-,8+/m1/s1

1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate - Physico-chemical Properties

Molecular FormulaC11H18FNO4
Molar Mass247.26
Density1.16
Melting Point34-39 °C
Boling Point296.5°C at 760 mmHg
Flash Point110°C
Water SolubilityInsoluble in water.
Vapor Presure0.00143mmHg at 25°C
Storage Condition2-8°C
Refractive Index1.465

1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate - Risk and Safety

WGK Germany3

1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate - Introduction

N-Boc-trans-4-fluoro-L-proline methyl ester is an organic compound whose chemical structural formula is N-Boc-trans-4-fluoro-l-prolin-och3.

N-Boc-trans-4-fluoro-L-proline methyl ester is a solid compound, usually colorless or slightly yellow crystal. It has good solubility and is soluble in some organic solvents, such as methanol and dimethylthionamide.

N-Boc-trans-4-fluoro-L-proline methyl ester has important applications in organic synthesis. It can be used as an intermediate in drug synthesis for the synthesis of physiologically active compounds. It has also been used to synthesize new drugs with antiviral and antitumor activity.

The preparation method of N-Boc-trans-4-fluoro-L-proline methyl ester is usually realized by reacting the existing trans-4-fluoro-L-proline with methanol and adding N-Boc protecting groups.

When using N-Boc-trans-4-fluoro-L-proline methyl ester in the laboratory, you need to pay attention to its safety. It is irritating and direct contact with skin and eyes should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. In addition, it should be operated in a well-ventilated place to avoid inhalation of vapors. Store it in a dry, cool place, away from fire and oxidizing agents.

In General, N-Boc-trans-4-fluoro-L-proline methyl ester is an organic compound with important application value, it is necessary to pay attention to safe operation when using it.
Last Update:2024-04-09 20:52:54
1-tert-Butyl  2-methyl  (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate
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CAS: 203866-18-6
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Mobile: +86-18621343501
QQ: 2881950922 Click to send a QQ message
Wechat: 18621343501
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Shanghai Macklin Biochemical Co., Ltd
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Product Name: N-Boc-|trans|-4-fluoro-L-proline methyl ester Visit Supplier Webpage Request for quotation
CAS: 203866-18-6
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
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View History
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