1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester
1-Boc-2-phenyl-4-piperidinone
CAS: 849928-30-9
Molecular Formula: C16H21NO3
1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester - Names and Identifiers
| Name | 1-Boc-2-phenyl-4-piperidinone |
| Synonyms | 1-Boc-2-Phenyl-4-piperidinone 1-Boc-2-phenyl-4-piperidinone 1-BOC-2-PHENYL-PIPERIDIN-4-ONE 1-Boc-2-Phenyl-Piperidin-4-One 1-N-BOC-2-PHENYL-PIPERIDIN-4-ONE 4-oxo-2-phenyl-1-piperidinecarboxylic acid tert-butyl ester 1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester |
| CAS | 849928-30-9 |
| EINECS | 200-589-5 |
| InChI | InChI=1/C16H21NO3/c1-16(2,3)20-15(19)17-10-9-13(18)11-14(17)12-7-5-4-6-8-12/h4-8,14H,9-11H2,1-3H3 |
1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester - Physico-chemical Properties
| Molecular Formula | C16H21NO3 |
| Molar Mass | 275.34 |
| Density | 1.122±0.06 g/cm3(Predicted) |
| Boling Point | 400.8±45.0 °C(Predicted) |
| pKa | -2.33±0.40(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.532 |
1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester - Introduction
It is an organic compound with the following properties and uses:
Nature:
-Appearance: colorless or light yellow crystal or crystal powder
-Molecular formula: C17H23NO3
-Molecular weight: 293.37g/mol
-Melting point: 60-64 ℃
-Boiling point: 402.9 ℃
-Solubility: Soluble in polar organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane
-Stability: stable, but should avoid contact with strong oxidants and strong acids
Use:
-is an important organic synthesis intermediate, widely used in the field of drug synthesis and organic synthesis
-It can be used to synthesize a variety of drugs and bioactive molecules, such as piperidine anticancer drugs and intermediates, potential neuroprotective agents, etc.
Preparation Method:
The preparation method can use the following steps:
1. benzoyl chloride and 4-piperidone react to generate N,N-dimethyl-N-(phenyl) formamide (N,N-dimethyl-N-(phenyl)methanamide).
2. The reaction of N-dimethyl-N-(phenyl) formamide and tert-butoxyformyl ammonium chloride is formed under the action of alkali.
Safety Information:
-may be irritating to the eyes, skin and respiratory tract. Use personal protective equipment such as safety glasses, gloves and respiratory protection.
-During operation and storage, care should be taken to prevent contact with oxidants and acids to avoid the risk of fire or explosion.
-Follow good laboratory practices and safe operating procedures to ensure the safe use of chemicals.
Nature:
-Appearance: colorless or light yellow crystal or crystal powder
-Molecular formula: C17H23NO3
-Molecular weight: 293.37g/mol
-Melting point: 60-64 ℃
-Boiling point: 402.9 ℃
-Solubility: Soluble in polar organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane
-Stability: stable, but should avoid contact with strong oxidants and strong acids
Use:
-is an important organic synthesis intermediate, widely used in the field of drug synthesis and organic synthesis
-It can be used to synthesize a variety of drugs and bioactive molecules, such as piperidine anticancer drugs and intermediates, potential neuroprotective agents, etc.
Preparation Method:
The preparation method can use the following steps:
1. benzoyl chloride and 4-piperidone react to generate N,N-dimethyl-N-(phenyl) formamide (N,N-dimethyl-N-(phenyl)methanamide).
2. The reaction of N-dimethyl-N-(phenyl) formamide and tert-butoxyformyl ammonium chloride is formed under the action of alkali.
Safety Information:
-may be irritating to the eyes, skin and respiratory tract. Use personal protective equipment such as safety glasses, gloves and respiratory protection.
-During operation and storage, care should be taken to prevent contact with oxidants and acids to avoid the risk of fire or explosion.
-Follow good laboratory practices and safe operating procedures to ensure the safe use of chemicals.
Last Update：2024-04-09 02:00:48
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Product Name: 1-BOC-2-PHENYL-PIPERIDIN-4-ONE Visit Supplier Webpage Request for quotationCAS: 849928-30-9
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Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
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Product Name: 1-Boc-2-Phenyl-4-piperidinone Visit Supplier Webpage Request for quotationCAS: 849928-30-9
Tel: +86-18821248368
Email: Int06@meryer.com
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QQ: 495145328
WhatsApp: +86-18821248368
Product Name: 1-BOC-2-PHENYL-PIPERIDIN-4-ONE Visit Supplier Webpage Request for quotation
CAS: 849928-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
CAS: 849928-30-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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View History
1-Piperidinecarboxylic acid, 4-oxo-2-phenyl-, 1,1-dimethylethyl ester
O-NPS-L-SERINE DICYCLOHEXYLAMINE SALT
3 - 溴-5 - 氯-2 - 氟-5 - 吡啶
4,4-Bis[3-Carboxy-5-Oxo-1-(4-Sulfophenyl)-2-Pyrazolin-4-YL]Pentamethine Oxonole Dipotassium Salt
N,N-DIETHYL-N-METHYL-N-(2-METHOXYETHYL)AMMONIUM BIS(TRIFLUOROMETHANE SULUFONYL)IMIDE
4-NITROSO-3,4-DIHYDROQUINOXALIN-2(1H)-ONE
2-(4-bromophenyl)-5-{[(2,4-dichlorophenyl)methyl]sulfanyl}-1,3,4-oxadiazole
7-methoxynaphthalen-2-ol
2-cyano-2-propenoic aci 2-methoxyethyl ester
2-nitro-3-(trifluoromethyl)aniline
O-NPS-L-SERINE DICYCLOHEXYLAMINE SALT
3 - 溴-5 - 氯-2 - 氟-5 - 吡啶
4,4-Bis[3-Carboxy-5-Oxo-1-(4-Sulfophenyl)-2-Pyrazolin-4-YL]Pentamethine Oxonole Dipotassium Salt
N,N-DIETHYL-N-METHYL-N-(2-METHOXYETHYL)AMMONIUM BIS(TRIFLUOROMETHANE SULUFONYL)IMIDE
4-NITROSO-3,4-DIHYDROQUINOXALIN-2(1H)-ONE
2-(4-bromophenyl)-5-{[(2,4-dichlorophenyl)methyl]sulfanyl}-1,3,4-oxadiazole
7-methoxynaphthalen-2-ol
2-cyano-2-propenoic aci 2-methoxyethyl ester
2-nitro-3-(trifluoromethyl)aniline