1-O-tert-butyl 3-O-methyl 5,5-difluoropiperidine-1,3-dicarboxylate
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate
CAS: 1255667-06-1
Molecular Formula: C12H19F2NO4
1-O-tert-butyl 3-O-methyl 5,5-difluoropiperidine-1,3-dicarboxylate - Names and Identifiers
1-O-tert-butyl 3-O-methyl 5,5-difluoropiperidine-1,3-dicarboxylate - Physico-chemical Properties
| Molecular Formula | C12H19F2NO4 |
| Molar Mass | 279.28 |
| Density | 1.19±0.1 g/cm3(Predicted) |
| Boling Point | 311.4±42.0 °C(Predicted) |
| pKa | -6.54±0.60(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD18433629 |
1-O-tert-butyl 3-O-methyl 5,5-difluoropiperidine-1,3-dicarboxylate - Introduction
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate is an organic compound with the chemical formula C12H18F2N2O4.
Nature:
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate is a colorless liquid with a special odor. It has a melting point of about -20°C and a boiling point of about 264°C. It is insoluble in water at room temperature, but soluble in many organic solvents, such as ethanol and dichloromethane.
Use:
The compound is mainly used as an intermediate in organic synthesis. It is widely used in the field of drug synthesis and pesticide synthesis. Because its structure contains piperidine and tert-butyl ester functional groups, it has high chemical reactivity.
Preparation Method:
1-tert-Butyl 3-methyl 5,5-difluopperidine-1, 3-dicarboxylate can be obtained by reacting piperidine with a fluorinating agent under appropriate conditions. The specific synthesis method can be optimized according to the specific needs, and the basic knowledge and technology of organic synthesis are generally required.
Safety Information:
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate is relatively safe for the human body under general conditions, but some safety precautions still need to be paid attention. It may be irritating to the eyes, skin and respiratory tract, so wear protective glasses, gloves and a mask during use. At the same time, avoid inhalation of its vapor and contact with the skin to avoid discomfort. In case of contact, flush the affected area immediately with plenty of water and seek medical attention. During storage and transportation, keep away from fire and flammable materials, and maintain a well-ventilated environment. Environmental, health and safety regulations and guidelines should be followed when using and handling this compound.
Nature:
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate is a colorless liquid with a special odor. It has a melting point of about -20°C and a boiling point of about 264°C. It is insoluble in water at room temperature, but soluble in many organic solvents, such as ethanol and dichloromethane.
Use:
The compound is mainly used as an intermediate in organic synthesis. It is widely used in the field of drug synthesis and pesticide synthesis. Because its structure contains piperidine and tert-butyl ester functional groups, it has high chemical reactivity.
Preparation Method:
1-tert-Butyl 3-methyl 5,5-difluopperidine-1, 3-dicarboxylate can be obtained by reacting piperidine with a fluorinating agent under appropriate conditions. The specific synthesis method can be optimized according to the specific needs, and the basic knowledge and technology of organic synthesis are generally required.
Safety Information:
1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate is relatively safe for the human body under general conditions, but some safety precautions still need to be paid attention. It may be irritating to the eyes, skin and respiratory tract, so wear protective glasses, gloves and a mask during use. At the same time, avoid inhalation of its vapor and contact with the skin to avoid discomfort. In case of contact, flush the affected area immediately with plenty of water and seek medical attention. During storage and transportation, keep away from fire and flammable materials, and maintain a well-ventilated environment. Environmental, health and safety regulations and guidelines should be followed when using and handling this compound.
Last Update：2024-04-09 21:04:16
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Spot supply
Product Name: 1-tert-butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate Visit Supplier Webpage Request for quotationCAS: 1255667-06-1
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 1-tert-Butyl 3-methyl 5,5-difluoropiperidine-1,3-dicarboxylate Visit Supplier Webpage Request for quotationCAS: 1255667-06-1
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
1-O-tert-butyl 3-O-methyl 5,5-difluoropiperidine-1,3-dicarboxylate
857838-55-2
Acetamide, 2-amino-N-[(3-bromophenyl)methyl]-N-cyclopropyl-
4-(2-fluoro-4-nitrophenoxy)-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine
(1α,5α)-8-Oxabicyclo[3.2.1]octa-6-ene-3-one
3-(5-methyl-3,4-dihydropyrazol-2-yl)benzenesulfonic acid
5-amino-1-[2-methyl-6-(3-methylphenoxy)-4-pyrimidinyl]-3-(methylsulfanyl)-1H-pyrazole-4-carbonitrile
3156-44-3
2-Amino-5-bromo-4-methylpyrimidine
3-Methylbenzenamine
857838-55-2
Acetamide, 2-amino-N-[(3-bromophenyl)methyl]-N-cyclopropyl-
4-(2-fluoro-4-nitrophenoxy)-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridine
(1α,5α)-8-Oxabicyclo[3.2.1]octa-6-ene-3-one
3-(5-methyl-3,4-dihydropyrazol-2-yl)benzenesulfonic acid
5-amino-1-[2-methyl-6-(3-methylphenoxy)-4-pyrimidinyl]-3-(methylsulfanyl)-1H-pyrazole-4-carbonitrile
3156-44-3
2-Amino-5-bromo-4-methylpyrimidine
3-Methylbenzenamine