1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole
CAS: 837392-62-8
Molecular Formula: C15H20BNO2
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE - Names and Identifiers
| Name | 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole |
| Synonyms | 1-Methyl-5-(4 AKOS BRN-1159 2-dioxaborolan-2-yl)-1H-indole 1-Methyl-5-indoleboronic acid pinacol ester 1-METHYLINDOLE-5-BORONIC ACID, PINACOL ESTER 1-Methyl-5-(4,4,5,5-tetramethyl-1,2,3-dioxaborolan-2-yl)-1H-indole 1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole 1-Methyl-5-indoleboronic acid pinacol ester, 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole |
| CAS | 837392-62-8 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C15H20BNO2/c1-14(2)15(3,4)19-16(18-14)12-6-7-13-11(10-12)8-9-17(13)5/h6-10H,1-5H3 |
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE - Physico-chemical Properties
| Molecular Formula | C15H20BNO2 |
| Molar Mass | 257.14 |
| Density | 1.05±0.1 g/cm3(Predicted) |
| Melting Point | 110-114 °C (lit.) |
| Boling Point | 391.3±15.0 °C(Predicted) |
| Flash Point | 190.466°C |
| Vapor Presure | 0mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.534 |
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| Hazard Note | Irritant |
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE - Introduction
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is an organic compound with the chemical formula C15H19BO2N. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a colorless or light yellow solid.
-Melting point: Its melting point range is about 70-75°C.
-Solubility: Soluble in some organic solvents, such as chloroform, ethanol, etc.
Use:
- 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is an important organic synthesis intermediate, commonly used in organic synthesis reactions.
-It can be used to construct a fused indole ring structure to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole can be prepared in many ways, one of which is commonly used:
-First, 1-methylindole is reacted with boronic acid diphenyl ester under alkaline conditions to obtain boronic acid methylindole ester.
-Then, the ester group in the boronic acid methyl indole ester is replaced with tetramethylborate (such as tetramethylborate) to obtain 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole.
Safety Information:
Nature:
-Appearance: 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is a colorless or light yellow solid.
-Melting point: Its melting point range is about 70-75°C.
-Solubility: Soluble in some organic solvents, such as chloroform, ethanol, etc.
Use:
- 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole is an important organic synthesis intermediate, commonly used in organic synthesis reactions.
-It can be used to construct a fused indole ring structure to synthesize biologically active compounds, such as drugs and pesticides.
Preparation Method:
1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole can be prepared in many ways, one of which is commonly used:
-First, 1-methylindole is reacted with boronic acid diphenyl ester under alkaline conditions to obtain boronic acid methylindole ester.
-Then, the ester group in the boronic acid methyl indole ester is replaced with tetramethylborate (such as tetramethylborate) to obtain 1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole.
Safety Information:
Last Update：2024-04-09 21:01:54
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Product Name: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole Visit Supplier Webpage Request for quotationCAS: 837392-62-8
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Product Name: 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole Visit Supplier Webpage Request for quotationCAS: 837392-62-8
Tel: +86-18821248368
Email: Int06@meryer.com
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Product Name: 1-Methyl-5-(4,4,5,5-TETRAMethyl-1,3,2-Dioxaborolan-2-YL)-1H-Indole Visit Supplier Webpage Request for quotation
CAS: 837392-62-8
Tel: 18301782025
Email: 3008007409@qq.com
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CAS: 837392-62-8
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View History
1-METHYL-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE
Pyrimidine,4-[(trimethylsilyl)oxy]-(9CI)
Pyrazino[1,2-a]indole,1-hydrazinyl-3,4-dihydro-8-methoxy-, hydrochloride (1:1)
Rythmol-d5
Fmoc-D-2,3-Dimethylphe
Aripiprazole Related CoMpound G
CYANIDIN 3-O-(6-O-MALONYL-Β-D-GLUCOSIDE)
Walphos SL-W012-1
1-Methyl-nicotinamide Iodide
(2-氟-5-(三氟甲基)苯基)(苯基)甲酮
Pyrimidine,4-[(trimethylsilyl)oxy]-(9CI)
Pyrazino[1,2-a]indole,1-hydrazinyl-3,4-dihydro-8-methoxy-, hydrochloride (1:1)
Rythmol-d5
Fmoc-D-2,3-Dimethylphe
Aripiprazole Related CoMpound G
CYANIDIN 3-O-(6-O-MALONYL-Β-D-GLUCOSIDE)
Walphos SL-W012-1
1-Methyl-nicotinamide Iodide
(2-氟-5-(三氟甲基)苯基)(苯基)甲酮