1-CBZ-2-AMINOMETHYL PYRROLIDINE

1-CBZ-2-AMINOMETHYL PYRROLIDINE - Names and Identifiers

Name	(S)-2-(Aminomethyl)-1-Cbz-pyrrolidine
Synonyms	1-CBZ-2-AMINOMETHYL PYRROLIDINE 4-AMINOMETHYL-1-N-CBZ-PIPERIDINE 1-N-CBZ-2-(AMINOMETHYL)PYRROLIDINE (S)-1-CBZ-2-AMINOMETHYLPYRROLIDINE (S)-2-(Aminomethyl)-1-Cbz-pyrrolidine (S)-1-N-CBZ-2-(AMINOMETHYL)PYRROLIDINE 4-(AMINOMETHYL)PIPERIDINE, N-CBZ PROTECTED benzyl 4-(aminomethyl)piperidine-1-carboxylate benzyl 2-(aminomethyl)pyrrolidine-1-carboxylate (S)-BENZYL-2-(AMINOMETHYL)PYRROLIDINE-1-CARBOXYLATE benzyl (2R)-2-(aminomethyl)piperidine-1-carboxylate benzyl (2S)-2-(aminomethyl)pyrrolidine-1-carboxylate 4-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER 2-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER (S)-2-AMINOMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER
CAS	119020-03-0
InChI	InChI=1/C13H18N2O2/c14-9-12-7-4-8-15(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10,14H2

1-CBZ-2-AMINOMETHYL PYRROLIDINE - Physico-chemical Properties

Molecular Formula	C13H18N2O2
Molar Mass	234.29
Density	1.155±0.06 g/cm3(Predicted)
Boling Point	370.5±25.0 °C(Predicted)
Flash Point	177.9°C
Vapor Presure	1.1E-05mmHg at 25°C
pKa	9.91±0.29(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,2-8°C
Refractive Index	1.56

1-CBZ-2-AMINOMETHYL PYRROLIDINE - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S39 - Wear eye / face protection.

1-CBZ-2-AMINOMETHYL PYRROLIDINE - Introduction

(S)-2-Aminomethyl-1-Cbz-pyrrolidine, also known as (S)-2-(aminomethyl)-1-methoxycarbonylphenylpyrrolidine, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is a white to pale yellow solid that can exist as crystals. It has a high melting and boiling point and is soluble in many common organic solvents such as dichloromethane and methanol.

Use:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is an important organic intermediate used in the synthesis of other compounds. It can be used as a starting material for the preparation of biologically active compounds, medicaments or pesticides. In addition, it can also be applied to asymmetric catalytic reactions in organic synthesis and can be used as a chiral reagent for stereoselective synthesis.

Preparation Method:
(S)-2-Aminomethyl-1-Cbz-pyrrolidine is usually prepared by chemical synthesis methods. The specific method includes reacting pyrrolidine with p-toluenesulfonyl chloride to obtain pyrrolidine carbonyl chloride, and then preparing (S)-2-aminomethyl-1-Cbz-pyrrolidine by acting on ammonia gas.

Safety Information:
When using (S)-2-Aminomethyl-1-Cbz-pyrrolidine, follow appropriate laboratory safety procedures. Because it is a chemical, care should be taken to avoid inhalation, ingestion, or contact with the skin and eyes. Personal protective equipment, including laboratory gloves, goggles and protective clothing, should be used during operation. When handling or disposing of (S)-2-aminomethyl-1-Cbz-pyrrolidine, comply with local environmental regulations and follow the instructions given in the relevant safety data sheet.

Last Update：2024-04-09 21:04:16