1-Bromo-3-chloro-2-fluorobenzene - Names and Identifiers
1-Bromo-3-chloro-2-fluorobenzene - Physico-chemical Properties
Molecular Formula | C6H3BrClF
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Molar Mass | 209.44 |
Density | 1.719±0.06 g/cm3(Predicted) |
Melting Point | 44 °C |
Boling Point | 197.9±20.0 °C(Predicted) |
Flash Point | 73.5°C |
Vapor Presure | 0.521mmHg at 25°C |
Appearance | Solid |
Color | White to pale yellow |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.55 |
1-Bromo-3-chloro-2-fluorobenzene - Risk and Safety
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
R51 - Toxic to aquatic organisms
R36 - Irritating to the eyes
R22 - Harmful if swallowed
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
1-Bromo-3-chloro-2-fluorobenzene - Introduction
It is an organic compound with the formula C6H3ClFBr. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: It is a colorless to pale yellow liquid.
-Density: about 1.8 g/mL.
-Boiling point: About 158-160 ° C.
-Melting point: About -14 ° C.
-Solubility: The compound is soluble in many organic solvents, such as alcohols, ethers and esters.
Use:
-It can be used as an important raw material and intermediate in organic synthesis.
-It can be used in the fields of drug synthesis, Pesticide Synthesis and dye synthesis.
-The compound can also be used as an additive for surfactants, preservatives and softeners.
Method:
-The preparation of phosphonium can be achieved through the three-step reaction of fluorination, chlorination and bromination.
-First, fluorinate a hydrogen atom on the benzene ring to generate 3-fluorobenzene.
-Then, 3-fluorobenzene is reacted with a chlorinating agent, and one of the fluorine atoms is replaced by chlorine to obtain 3-chloro-2-fluorobenzene.
-Finally, 3-chloro-2-fluorobenzene reacts with a brominating agent, and one of the chlorine atoms is replaced by bromine to make a fluorobenzene.
Safety Information:
-A irritant to the skin and eyes, should immediately after contact with plenty of water rinse the corresponding parts.
-Avoid inhaling its vapor or contacting its liquid when using this compound.
-Follow relevant safety procedures during handling and storage, including wearing protective gloves and glasses.
-It is recommended to operate in a well-ventilated place to avoid high-concentration vapor.
-If necessary, it should be operated under a special chemical exhaust cabinet.
Last Update:2024-04-09 21:01:54