1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester
4-Boc-Piperazine-3-carboxylic acid
CAS: 1214196-85-6
Molecular Formula: C10H18N2O4
1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester - Names and Identifiers
| Name | 4-Boc-Piperazine-3-carboxylic acid |
| Synonyms | 1-Boc-2-Piperazinecarboxylic acid 4-Boc-Piperazine-3-carboxylic acid 1-Boc-piperazine-2-Carbocylic acid 1-Boc-piperazine-2-carboxylic acid 4-Boc-Piperazine-3-carboxylic acidd 1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester 1-[(2-methylpropan-2-yl)oxycarbonyl]piperazine-2-carboxylic acid 1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-2-piperazinecarboxylic acid |
| CAS | 1214196-85-6 |
| InChI | InChI=1S/C10H18N2O4/c1-10(2,3)16-9(15)12-5-4-11-6-7(12)8(13)14/h7,11H,4-6H2,1-3H3,(H,13,14) |
1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester - Physico-chemical Properties
| Molecular Formula | C10H18N2O4 |
| Molar Mass | 230.26 |
| Density | 1.193±0.06 g/cm3(Predicted) |
| Boling Point | 371.8±37.0 °C(Predicted) |
| pKa | 2.90±0.20(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester - Introduction
4-N-Boc-3-piperazinecarboxylic acid is an organic compound with the chemical name N-(tert-Butoxycarbonyl)-3-piperidinemethanoic acid(N-(Boc)-3-piperidinemethanoic acid). The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
4-N-Boc-3-piperazinecarboxylic acid is a white crystalline solid with a molecular weight of 215.24g/mol. It can be stable at room temperature. The compound has strong acidity.
Use:
4-N-Boc-3-piperazinecarboxylic acid is widely used in organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds, such as key intermediates in the synthesis of drugs and pesticides. It can also be used in the synthesis of other amide compounds.
Preparation Method:
The preparation of 4-N-Boc-3-piperazinecarboxylic acid generally involves two steps. First, piperazine is reacted with isocyanate to introduce a protecting group (tert-butoxycarbonyl) to form N-tert-Boc-3-piperazine-carboxylic acid isocyanurate. The isocyanate is then converted to the target 4-N-Boc-3-piperazinecarboxylic acid by a hydrolysis reaction.
Safety Information:
The safety of 4-N-Boc-3-piperazinecarboxylic acid has not been fully studied, so relevant safety procedures should be followed when using it. It may cause irritation to the skin, eyes and respiratory system, so it is recommended to wear personal protective equipment to avoid direct contact. In addition, the compound should be stored and handled properly to avoid contact with flammable substances, oxidizing agents and strong acids and bases to reduce safety risks.
Nature:
4-N-Boc-3-piperazinecarboxylic acid is a white crystalline solid with a molecular weight of 215.24g/mol. It can be stable at room temperature. The compound has strong acidity.
Use:
4-N-Boc-3-piperazinecarboxylic acid is widely used in organic synthesis. It can be used as an intermediate in the synthesis of other organic compounds, such as key intermediates in the synthesis of drugs and pesticides. It can also be used in the synthesis of other amide compounds.
Preparation Method:
The preparation of 4-N-Boc-3-piperazinecarboxylic acid generally involves two steps. First, piperazine is reacted with isocyanate to introduce a protecting group (tert-butoxycarbonyl) to form N-tert-Boc-3-piperazine-carboxylic acid isocyanurate. The isocyanate is then converted to the target 4-N-Boc-3-piperazinecarboxylic acid by a hydrolysis reaction.
Safety Information:
The safety of 4-N-Boc-3-piperazinecarboxylic acid has not been fully studied, so relevant safety procedures should be followed when using it. It may cause irritation to the skin, eyes and respiratory system, so it is recommended to wear personal protective equipment to avoid direct contact. In addition, the compound should be stored and handled properly to avoid contact with flammable substances, oxidizing agents and strong acids and bases to reduce safety risks.
Last Update：2024-04-09 21:01:54
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CAS: 1214196-85-6
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View History
1,2-Piperazinedicarboxylic acid, 1-(1,1-diMethylethyl) ester
Ethanol, 2-[(4,6-di-1-pyrrolidinyl-1,3,5-triazin-2-yl)amino]-
11-cis-13,14-Dihydro Retinol
Diphenyl[α-(2-piperidinoethyl)benzyl]phosphine oxide
4-chloro-N-{4-[(mesitylamino)sulfonyl]phenyl}benzamide
2-[(4,5-Diamino-1-naphthyl)azo]-5-nitrobenzenesulfonic acid
Benzoic acid, 5-mercapto-2-nitro-
rel-(3R,4S)-3-Amino-4-chlorotetrahydrothiophene 1,1-dioxide hydrochloride
128452-54-0
3-Desmethyl 4-Methyl Meclizine Dihydrochloride
Ethanol, 2-[(4,6-di-1-pyrrolidinyl-1,3,5-triazin-2-yl)amino]-
11-cis-13,14-Dihydro Retinol
Diphenyl[α-(2-piperidinoethyl)benzyl]phosphine oxide
4-chloro-N-{4-[(mesitylamino)sulfonyl]phenyl}benzamide
2-[(4,5-Diamino-1-naphthyl)azo]-5-nitrobenzenesulfonic acid
Benzoic acid, 5-mercapto-2-nitro-
rel-(3R,4S)-3-Amino-4-chlorotetrahydrothiophene 1,1-dioxide hydrochloride
128452-54-0
3-Desmethyl 4-Methyl Meclizine Dihydrochloride