1,2,4-Oxadiazole-5-methanamine, 3-phenyl-

1,2,4-Oxadiazole-5-methanamine, 3-phenyl- - Names and Identifiers

Name	(3-phenyl-1,2,4-oxadiazol-5-yl)methanamine
Synonyms	AKOS BB-7187 ASINEX-REAG BAS 08768035 1,2,4-Oxadiazole-5-methanamine, 3-phenyl- (3-phenyl-1,2,4-oxadiazol-5-yl)methanamine (3-Phenyl-1,2,4-oxadiazol-5-yl)methylamine 1-(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine METHYL-(3-PHENYL-[1,2,4]OXADIAZOL-5-YL)-AMINE C-(3-PHENYL-[1,2,4]OXADIAZOL-5-YL)-METHYLAMINE
CAS	90564-77-5
InChI	InChI=1/C9H9N3O/c10-6-8-11-9(12-13-8)7-4-2-1-3-5-7/h1-5H,6,10H2

1,2,4-Oxadiazole-5-methanamine, 3-phenyl- - Physico-chemical Properties

Molecular Formula	C9H9N3O
Molar Mass	175.19
Density	1.217g/cm³
Melting Point	>170°C (dec.)
Boling Point	325.5°C at 760 mmHg
Flash Point	150.7°C
Solubility	DMSO (Slightly), Methanol (Very Slightly)
Vapor Presure	0.000229mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	2-8°C
Stability	Hygroscopic
Refractive Index	1.578

1,2,4-Oxadiazole-5-methanamine, 3-phenyl- - Risk and Safety

Risk Codes	25 - Toxic if swallowed
Safety Description	45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

1,2,4-Oxadiazole-5-methanamine, 3-phenyl- - Introduction

(3-phenyl-1,2,4-oxadiazol-5-yl)methanamine ((3-phenyl-1,2,4-oxadiazol-5-yl)methanamine), often abbreviated as POAm, is an organic compound.

Nature:
POAm is a solid with white or pale yellow crystals. It has a relatively low melting and boiling point and is readily soluble in commonly used organic solvents, such as ethanol and dimethylformamide. The compound is relatively stable in air.

Use:
POAm is a useful synthetic intermediate compound, which can be used to synthesize new compounds with various nitrogen-containing ring structures. It is commonly used in the field of medicine, for the preparation of antibacterial, antiviral, anti-tumor drugs. In addition, POAm can also be used in the field of materials science for the preparation of polymers and polymer composites with special functions and properties.

Method:
POAm is prepared by a variety of methods, and is usually synthesized by a two-step method. First, benzaldehyde and sodium cyanide react under alkaline conditions to form phenylthiourea. Phenylthiourea is then reacted with chloromethanol to produce POAm. The reaction can be carried out at room temperature, and the reaction time is short.

Safety Information:
POAm generally has no special hazards under normal use conditions, but it is a chemical and should comply with relevant safety procedures. Appropriate protective equipment such as lab gloves, goggles, etc. shall be worn during operation. Avoid POAm contact with skin, inhalation or ingestion. In case of accidental contact, rinse immediately with plenty of water and seek medical examination. At the same time, POAm should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.

Last Update：2024-04-09 21:11:58