(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan
Hydroquinine 9-Phenanthryl Ether
CAS: 135096-78-5
Molecular Formula: C34H34N2O2
(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan - Names and Identifiers
| Name | Hydroquinine 9-Phenanthryl Ether |
| Synonyms | O-(9-PHENANTHRYL)HYDROQUININE HYDROQUININE 9-PHENANTHRYL ETHER Hydroquinine 9-Phenanthryl Ether (8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan (8α,9R)-10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-Cinchonan Cinchonan, 10,11-dihydro-6'-Methoxy-9-(9-phenanthrenyloxy)-, (8α,9R)- (2S,4S,5R)-5-Ethyl-2-((R)-(6-methoxyquinolin-4-yl)(phenanthren-9-yloxy)methyl)quinuclidine |
| CAS | 135096-78-5 |
(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan - Physico-chemical Properties
| Molecular Formula | C34H34N2O2 |
| Molar Mass | 502.65 |
| Density | 1.24±0.1 g/cm3(Predicted) |
| Melting Point | 120°C (dec.)(lit.) |
| Boling Point | 690.3±40.0 °C(Predicted) |
| BRN | 4848702 |
| pKa | 9?+-.0.70(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | 1544 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 9 |
| HS Code | 29392000 |
| Hazard Class | 6.1(b) |
| Packing Group | III |
(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan - References
| Overview | hydrogenated Quinine Alkaloids. Soluble in hot ethanol, slightly soluble in water and ether, its hydrochloride is small flake Crystal, soluble in methanol, chloroform, slightly soluble in water or ethanol, difficult to dissolve in acetic acid. It is an antiarrhythmic drug with similar effect to quinidine and slightly lower oral toxicity than quinidine. |
| Use | hydroquinidine is also an important pharmaceutical intermediate, but there are few reports on its preparation methods, the product yield of the existing method is low, and the preparation cost is high. Hydrogenated quinuclidin-9-phenanthryl ether is a novel class of quinidine Quinine Alkaloids. |
Last Update：2024-04-09 21:11:58
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View History
(8α,9R)-10,11-Dihydro-6'-methoxy-9-(9-phenanthrenyloxy)cinchonan
23313-21-5
130523-93-2
EOS-60696
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66695-86-1
Oxazole, 2-(2,6-difluorophenyl)-4,5-dihydro-4-(2,3,4,5,6-pentamethylphenyl)-
1046832-00-1
89673-52-9
1-(4-Bromo-phenoxymethyl)-1H-pyrazole-3-
23313-21-5
130523-93-2
EOS-60696
chlorine perchlorate
66695-86-1
Oxazole, 2-(2,6-difluorophenyl)-4,5-dihydro-4-(2,3,4,5,6-pentamethylphenyl)-
1046832-00-1
89673-52-9
1-(4-Bromo-phenoxymethyl)-1H-pyrazole-3-