(5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol - Names and Identifiers
Name | (5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol
|
Synonyms | 2H-1,2,3-Triazole-4-methanol, 5-methyl-2-phenyl- (5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol (5-METHYL-2-PHENYL-2H-1,2,3-TRIAZOL-4-YL)METHANOL
|
CAS | 13322-19-5
|
InChI | InChI=1/C10H11N3O/c1-8-10(7-14)12-13(11-8)9-5-3-2-4-6-9/h2-6,14H,7H2,1H3 |
(5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol - Physico-chemical Properties
Molecular Formula | C10H11N3O
|
Molar Mass | 189.21 |
Density | 1.23±0.1 g/cm3(Predicted) |
Melting Point | 75 °C |
Boling Point | 392.0±34.0 °C(Predicted) |
Flash Point | 190.9°C |
Vapor Presure | 7.58E-07mmHg at 25°C |
pKa | 12.99±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.626 |
(5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol - Risk and Safety
Safety Description | S24/25 - Avoid contact with skin and eyes.
|
(5-methyl-2-phenyl-2H-1,2,3-triazol-4-yl)methanol - Introduction
(5-Methyl-2-phenyl-2H-1, 2,3-thiazol-4-yl) methanol, also known as MTSM, is a commonly used reagent and intermediate in organic synthesis. The following is a description of the nature, use, method and safety information of MTSM:
1. nature:
-Appearance: MTSM is a white crystalline solid.
-Molecular formula: C10H9NOS.
-Molecular weight: 203.25g/mol.
-Solubility: MTSM is soluble in some organic solvents, such as methanol, ethanol and dimethylformamide.
2. use:
-Synthetic intermediates: MTSM can be used to prepare various organic compounds, such as drugs, pesticides and dyes.
-Aldehyde group protective agent: MTSM can be used as an aldehyde group protective agent for organic synthesis reactions.
-Chemical reaction catalyst: MTSM can be used as a catalyst to participate in some chemical reactions, such as the reaction of the solution.
3. Preparation method:
The preparation method of MTSM can be carried out through the following steps:
-First, p-methylene aniline is reacted with carbon sulfide to generate p-methylene aniline thiosodium salt.
-Then, the salt is reacted with an alcohol to obtain methylene phenyl thiazole.
-Finally, methylene phenyl thiazole is reacted with methanol to synthesize (5-methyl-2-phenyl-2H-1, 2,3-thiazol-4-yl) methanol.
4. Safety Information:
- MTSM may be irritating and harmful, and care should be taken to avoid skin and eye contact. Wear appropriate personal protective equipment, such as lab gloves and goggles.
-When handling and storing MTSM, avoid contact with oxidants and strong acids to avoid dangerous reactions.
-It is recommended to use MTSM in a well-ventilated laboratory environment to avoid inhalation of dust or gas.
-When using or disposing of MTSM, operate in accordance with local regulations and safe operating procedures to avoid harm to humans and the environment.
Last Update:2024-04-09 21:01:54