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(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER

tert-Butyl N-[4-(aminomethyl)phenyl]carbamate

CAS: 220298-96-4

Molecular Formula: C12H18N2O2

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(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER - Names and Identifiers

Name tert-Butyl N-[4-(aminomethyl)phenyl]carbamate
Synonyms 4-(Aminomethy)-1-N-Boc-Aniline
4-(Aminomethyl)-1-N-Boc-aniline
4-(AMINOMETHYL)-1-N-BOC-ANILINE
2-(4-CHLOROPHENOXY)MALONDIALDEHYDE
4-(TERT-BUTOXYCARBONYLAMINO)BENZYLAMINE
4-(tert-Butoxycarbonylamino)benzylamine
TERT-BUTYL 4-(AMINOMETHYL)PHENYL CARBAMATE
tert-butyl [4-(aminomethyl)phenyl]carbamate
TERT-BUTYL N-[4-(AMINOMETHYL)PHENYL]CARBAMATE
tert-Butyl N-[4-(aminomethyl)phenyl]carbamate
(4-AMINOMETHYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
CAS 220298-96-4
InChI InChI=1/C12H18N2O2/c1-12(2,3)16-11(15)14-10-6-4-9(8-13)5-7-10/h4-7H,8,13H2,1-3H3,(H,14,15)

(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER - Physico-chemical Properties

Molecular FormulaC12H18N2O2
Molar Mass222.28
Density1.120±0.06 g/cm3(Predicted)
Melting Point64-68°C(lit.)
Boling Point300.1±25.0 °C(Predicted)
Flash Point135.3°C
Vapor Presure0.00114mmHg at 25°C
pKa13.68±0.70(Predicted)
Storage ConditionRoom Temprature
Refractive Index1.564
MDLMFCD02183573

(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER - Risk and Safety

Risk CodesR36/37/38 - Irritating to eyes, respiratory system and skin.
R34 - Causes burns
R22 - Harmful if swallowed
R43 - May cause sensitization by skin contact
Safety DescriptionS26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S22 - Do not breathe dust.
S36/37 - Wear suitable protective clothing and gloves.
WGK Germany3
Hazard ClassIRRITANT

(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER - Introduction

tert-Butyl N-[4-(aminomethyl)phenyl]carbamate is an organic compound with the chemical formula C15H22N2O2. The following describes its nature, use, preparation and safety information.

Nature:
tert-Butyl N-[4-(aminomethyl)phenyl]carbamate is a solid, white crystalline powder at room temperature. It has low solubility and can be dissolved in organic solvents (such as chloroform, dimethylformamide). It is a stable compound with a long retention period when stored under dry conditions.

Use:
tert-Butyl N-[4-(aminomethyl)phenyl]carbamate is commonly used in some reactions and catalytic processes in organic synthesis. It can be used as a raw material or intermediate for the synthesis of biologically active compounds or drugs. It has certain application potential in the field of medicinal chemistry and pharmaceutical research.

Method:
The preparation method of tert-Butyl N-[4-(aminomethyl)phenyl]carbamate can be carried out by the following steps:
1. First, Aniline reacts with formaldehyde to generate aminomethyl compounds.
2. Next, the obtained aminomethyl compound is reacted with tert-butyl chloroformate to generate the tert-Butyl N-[4-(aminomethyl)phenyl]carbamate.

Safety Information:
tert-Butyl N-[4-(aminomethyl)phenyl]carbamate currently has no clear toxicity data reported, general laboratory safety practices should be followed. It may cause irritation to the eyes, skin and respiratory system. Wear appropriate protective equipment such as lab gloves and goggles during use. In case of accidental spilling or inhalation, rinse immediately with water and seek medical help.

Please note that the above information is for reference only. Please be familiar with the safety information and handling methods of the relevant compounds before operation, and operate in a suitable laboratory environment.
Last Update:2024-04-09 21:01:54
(4-AMINOMETHYL-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
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