(3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol - Names and Identifiers
Name | (3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol
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Synonyms | (3S (3S,4S)-1-Benzylpyrrolidine-3,4-diol (3S,4S)-1-BENZYL-PYRROLIDINE-3,4-DIOL (3S,4S)-(+)-1-BENZYL-3,4-PYRROLIDINDIOL (3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol (3S,4S)-(+)-1-BENZYL-3,4-PYRROLIDINEDIOL (3S,4S)-1-benzyl-3,4-dihydroxy-pyrrolidine (3S,4S)-1-benzyl-3,4-dihydroxypyrrolidinium (3S,4S)-1-(phenylMethyl)-3,4-Pyrrolidinediol 3,4-Pyrrolidinediol, 1-(phenylmethyl)-, (3S,4S)-
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CAS | 90365-74-5
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InChI | InChI=1/C11H15NO2/c13-10-7-12(8-11(10)14)6-9-4-2-1-3-5-9/h1-5,10-11,13-14H,6-8H2/p+1/t10-,11-/m0/s1 |
InChIKey | QJRIUWQPJVPYSO-QWRGUYRKSA-N |
(3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol - Physico-chemical Properties
Molecular Formula | C11H15NO2
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Molar Mass | 193.24 |
Density | 1.0945 (rough estimate) |
Melting Point | 94-100°C |
Boling Point | 329.46°C (rough estimate) |
Specific Rotation(α) | 33.6 º (c=1.05% in methanol) |
Flash Point | 195.1°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 1.08E-05mmHg at 25°C |
Appearance | Powder, Crystals, and/or Chunks |
Color | Off-white to yellow to light brown |
BRN | 4992458 |
pKa | 13.99±0.40(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.5041 (estimate) |
MDL | MFCD01073893 |
(3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 3 |
FLUKA BRAND F CODES | 10-34 |
HS Code | 29339900 |
(3S,4S)-(+)-1-Benzyl-3,4-pyrrolidindiol - Introduction
(3S,4S)-( )-1-Benzyl-3,4-pyrrolidindiol is an organic compound with the formula C13H17NO2. Its nature, use, formulation and safety information are described below.
Nature:
(3S,4S)-( )-1-Benzyl-3,4-zirrolidindiol is a colorless crystalline solid with a special three-dimensional structure. It is soluble in some organic solvents, such as ethanol and dichloromethane.
Use:
(3S,4S)-( )-1-Benzyl-3, 4-Pyrrolidindiol is a chiral compound, commonly used as a catalyst and ligand in organic synthesis. It can be used as a chiral inducer for the synthesis of chiral compounds and intermediates of drugs. In addition, it can also be used to prepare pyrrolidone (pyrrolidinone) compounds, which have important applications in pharmaceutical research and the pharmaceutical industry.
Method:
The synthesis of (3S,4S)-( )-1-Benzyl-3,4-zirrolidindiol can be achieved by various methods. One common method is by reduction of pyrrolidine with a chiral reducing agent. By this method, the product can be obtained with high selectivity and high yield.
Safety Information:
(3S,4S)-( )-1-Benzyl-3,4-Pyrrolidindiol is generally relatively safe under normal conditions of use, but care should be taken to comply with laboratory safety practices. It may be irritating to the eyes, skin and respiratory system, so wear gloves, goggles and a protective mask when used. In addition, it should be stored in a cool, dry and well-ventilated place, away from fire and combustibles. In case of accidental inhalation or contact, seek medical assistance immediately.
Last Update:2024-04-09 20:52:54