(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid

(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid - Names and Identifiers

Name	[2,3,5,6-tetrafluoro-4-(1-methylethoxy)phenyl]boronic acid
Synonyms	(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid (2,3,5,6-tetrafluoro-4-propan-2-yloxyphenyl)boronic acid [2,3,5,6-TETRAFLUORO-4-(1-METHYLETHOXY)PHENYL]BORONIC ACID [2,3,5,6-tetrafluoro-4-(1-methylethoxy)phenyl]boronic acid Boronic acid, B-[2,3,5,6-tetrafluoro-4-(1-methylethoxy)phenyl]-
CAS	871126-28-2
InChI	InChI=1/C9H9BF4O3/c1-3(2)17-9-7(13)5(11)4(10(15)16)6(12)8(9)14/h3,15-16H,1-2H3

(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid - Physico-chemical Properties

Molecular Formula	C9H9BF4O3
Molar Mass	251.97
Density	1.38g/cm³
Melting Point	138-142
Boling Point	306.6°C at 760 mmHg
Flash Point	139.2°C
Vapor Presure	0.000333mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.455

(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid - Risk and Safety

Hazard Symbols	C - Corrosive
WGK Germany	3

(2,3,5,6-Tetrafluoro-4-isopropoxyphenyl)-boronic acid - Introduction

[2,3,5,6-tetrafluoro-4-(1-methyllethoxy) phenyl]boronic acid is an organic compound whose chemical formula is C10H12BF4O2. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: solid powder
-Melting point: about 132-136°C
-Solubility: Soluble in common organic solvents such as methanol, ethanol and dimethylformamide

Use:
- [2,3,5,6-tetrafluoro-4-(1-methyllethoxy) phenyl]boronic acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used as a substrate for copper-catalyzed Suzuki coupling reactions for the construction of carbon-carbon bonds and carbon-boron bonds.
-The compound can also be used to prepare drugs, pesticides and various organic functional materials.

Preparation Method:
[2,3,5,6-tetrafluoro-4-(1-methyllethoxy) phenyl] The preparation method of boronic acid is relatively complicated and generally involves a series of organic synthesis steps. The main synthetic route is through the substitution reaction of phenylboronic acid with 2,3,5,6-tetrafluorophenol, and then the ester hydrolysis reaction under appropriate conditions to obtain the target product.

Safety Information:
- [2,3,5,6-tetrafluoro-4-(1-methyllethoxy) phenyl]boronic acid has acceptable safety under normal conditions of use and storage. However, although this compound has limited toxicity data, it should be used with caution.
-Chemical protective gloves, eye protection and protective clothing are recommended for operation. If skin contact or ingestion occurs, the affected area should be cleaned promptly and medical assistance should be sought immediately.
-In addition, for safety reasons, it should be stored in a dry, cool place, and away from open flames and fire sources.

Last Update：2024-04-09 20:52:54