伏立康唑中间体-2

伏立康唑中间体-2 - Names and Identifiers

Name	(2r,3s\|2s,3r)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1h-1,2,4-triazol-1-yl)butan-2-ol
Synonyms	N-1STEP Voriconazole Impurity 1 Voriconazole Impurity 12 Voriconazole USP Related Compound A (2RS,3RS)-α-(2,4-Difluorophenyl)-5-fluoro-β-Methyl-α-(1H-1,2,4-triazol-1-ylMethyl)-4-pyriMidineethanol
CAS	182230-43-9
EINECS	605-961-5
InChI	InChI=1/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m1/s1

伏立康唑中间体-2 - Physico-chemical Properties

Molecular Formula	C16H14F3N5O
Molar Mass	349.31
Density	1.42±0.1 g/cm3(Predicted)
Melting Point	123-128°C (dec.)
Boling Point	508.6±60.0 °C(Predicted)
Solubility	Chloroform (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
pKa	11.54±0.29(Predicted)
Storage Condition	2-8°C
Refractive Index	1.617

伏立康唑中间体-2 - Risk and Safety

HS Code

2933997500

伏立康唑中间体-2 - Introduction

Nature:
(2R,3S | 2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1, 2,4-triazol-1-yl)-2-butanol is a chiral compound. It is a solid with a specific molecular structure and spatial configuration. Specific physicochemical properties (such as melting point, boiling point, etc.) may require laboratory testing to determine.

Use:
(2R,3S | 2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1, 2,4-triazol-1-yl)-2-butanol may have some fields of application. According to its structural characteristics, it may be used in drug research and development, organic synthesis, chemical reaction exploration and so on. However, the specific use needs further research and experimental verification.

Method:
(2R,3S | 2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl) the preparation method of -1-(1H-1, 2,4-triazol-1-yl)-2-butanol may require the support of organic synthesis technology. The specific preparation method may depend on factors such as reaction conditions, raw material selection and catalyst.

Safety Information:

Last Update：2024-04-09 20:45:29