乙基5-氧代吡咯烷-2-甲酸酯
ethyl 5-oxo-DL-prolinate
CAS: 66183-71-9
Molecular Formula: C7H11NO3
乙基5-氧代吡咯烷-2-甲酸酯 - Names and Identifiers
| Name | ethyl 5-oxo-DL-prolinate |
| Synonyms | ethyl 5-oxoprolinate (±)-5-Oxoproline ethyl Ethyl DL-pyroglutaMate Ethyl DL-pyroglutamate 5-Oxo-DL-Proline ethyl ethyl 5-oxo-L-prolinate ethyl 5-oxo-DL-prolinate Ethyl 5-oxo-DL-prolinate Proline, 5-oxo-, ethyl ester ethyl 5-oxopyrrolidine-2-carboxylate |
| CAS | 66183-71-9 |
| EINECS | 266-226-9 |
| InChI | InChI=1/C7H11NO3/c1-2-11-7(10)5-3-4-6(9)8-5/h5H,2-4H2,1H3,(H,8,9)/t5-/m0/s1 |
乙基5-氧代吡咯烷-2-甲酸酯 - Physico-chemical Properties
| Molecular Formula | C7H11NO3 |
| Molar Mass | 157.17 |
| Density | 1.161±0.06 g/cm3(Predicted) |
| Melting Point | 54 °C |
| Boling Point | 137-140 °C(Press: 0.45 Torr) |
| Flash Point | 142.9°C |
| Vapor Presure | 0.000519mmHg at 25°C |
| pKa | 14.78±0.40(Predicted) |
| Storage Condition | Room Temprature |
| Refractive Index | 1.466 |
乙基5-氧代吡咯烷-2-甲酸酯 - Introduction
Ethyl 5-oxo-DL-prolinate is an organic compound with the chemical formula C7H11NO3. It is an ethyl ester derivative of pyroglutamic acid and contains an ester group in the chemical structure.
ethyl 5-oxo-DL-prolinate is a colorless solid with a weak characteristic odor. It is insoluble in water but can be dissolved in organic solvents such as alcohols, ethers and esters.
Ethyl 5-oxo-DL-prolinate has certain uses in the fields of chemistry and medicine. It can be used as a starting material and intermediate in chemical synthesis, and used in the synthesis of other complex organic compounds. In addition, it is also used as an additive in pharmaceutical formulations to enhance the stability and solubility of the drug.
The method of preparing ethyl 5-oxo-DL-prolinate is usually carried out by reacting pyroglutamic acid with acetic anhydride. The reaction is usually carried out under acidic conditions and at an appropriate temperature, and usually requires neutralization and purification steps to obtain a pure product.
Regarding safety information, ethyl 5-oxo-DL-prolinate has certain toxicity, and care should be taken to avoid direct contact with skin, eyes and respiratory system. Appropriate precautions, such as wearing protective gloves, goggles and respirators, should be taken during use and handling. During storage, it should be stored in a closed container, away from fire and oxidizing agents. In the event of accidental exposure or ingestion of this substance, seek medical attention immediately.
ethyl 5-oxo-DL-prolinate is a colorless solid with a weak characteristic odor. It is insoluble in water but can be dissolved in organic solvents such as alcohols, ethers and esters.
Ethyl 5-oxo-DL-prolinate has certain uses in the fields of chemistry and medicine. It can be used as a starting material and intermediate in chemical synthesis, and used in the synthesis of other complex organic compounds. In addition, it is also used as an additive in pharmaceutical formulations to enhance the stability and solubility of the drug.
The method of preparing ethyl 5-oxo-DL-prolinate is usually carried out by reacting pyroglutamic acid with acetic anhydride. The reaction is usually carried out under acidic conditions and at an appropriate temperature, and usually requires neutralization and purification steps to obtain a pure product.
Regarding safety information, ethyl 5-oxo-DL-prolinate has certain toxicity, and care should be taken to avoid direct contact with skin, eyes and respiratory system. Appropriate precautions, such as wearing protective gloves, goggles and respirators, should be taken during use and handling. During storage, it should be stored in a closed container, away from fire and oxidizing agents. In the event of accidental exposure or ingestion of this substance, seek medical attention immediately.
Last Update：2024-04-09 20:02:46
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View History
乙基5-氧代吡咯烷-2-甲酸酯
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2-羟基-3,5-二硝基苯甲酸甲酯
2-[(3-氯-2-甲基苯基)氨基]苯甲酸
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2-氨基-1-(4-氟苯基)乙酮盐酸盐
3-苯基吡咯烷-2-羧酸
RGFP 109 N-[6-(2-Aminophenylamino)-6-oxohexyl]-4-methylbenzamide
[3-[(2-甲基-1-氧代-2-丙烯基)氨基]苯基]硼酸均聚物
[2-(2-氟苯基)-2-氧代-乙基]丙二腈
3-(4-氟-苯硫基甲基)-哌啶盐酸盐
2-羟基-3,5-二硝基苯甲酸甲酯
2-[(3-氯-2-甲基苯基)氨基]苯甲酸
(R)-2-(4-羟基苯基)-2-新戊酰氨基乙酸 (阿莫西林杂质)
2-氨基-1-(4-氟苯基)乙酮盐酸盐
3-苯基吡咯烷-2-羧酸
RGFP 109 N-[6-(2-Aminophenylamino)-6-oxohexyl]-4-methylbenzamide
[3-[(2-甲基-1-氧代-2-丙烯基)氨基]苯基]硼酸均聚物
[2-(2-氟苯基)-2-氧代-乙基]丙二腈