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FMoc-Val-Cit-PAB-PNP

FMoc-Val-Cit-PAB-PNP

CAS: 863971-53-3

Molecular Formula: C40H42N6O10

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FMoc-Val-Cit-PAB-PNP - Names and Identifiers

Name FMoc-Val-Cit-PAB-PNP
Synonyms Moc-Val-Cit-PAB-PNP
FMoc-Val-Cit-PAB-PNP
FMOC-VAL-CIT-PAB-PNP (9-FLUORENYLMETHYLOXYCARBONYL-VALYL-CITRULLYL-(4-AMINOBENZYL)-(4-NITROPHENYL)CARBONATE)
L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-
{4-[(2S)-5-(carbamoylamino)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]pentanamido]phenyl}methyl 4-nitrophenyl carbonate
4-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]-[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
(9H-fluoren-9-yl)methyl ((S)-3-methyl-1-(((S)-1-((4-((((4-nitrophenoxy)carbonyl)oxy)methyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-1-oxobutan-2-yl)carbamate
CAS 863971-53-3

FMoc-Val-Cit-PAB-PNP - Physico-chemical Properties

Molecular FormulaC40H42N6O10
Molar Mass766.8
Density1.335±0.06 g/cm3(Predicted)
Melting Point189 °C(dec.)
Boling Point1024.0±65.0 °C(Predicted)
Solubility DMSO: ≥ 40 mg/mL
pKa10.63±0.46(Predicted)
Storage Condition2-8°C(protect from light)
Physical and Chemical PropertiesBioactive Fmoc-Val-Cit-PAB-PNP is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
UseApplication FMoc-Val-Cit-PAB-PNP is an organic intermediate, which can be used to prepare polypeptide conjugates.

FMoc-Val-Cit-PAB-PNP - Upstream Downstream Industry

Raw MaterialsBIS(4-NITROPHENYL) CARBONATE
4-Aminobenzyl alcohol
4-Nitrophenyl chloroformate
FMOC-L-Valine
L-Citrulline
L-Ornithine, N5-(aMinocarbonyl)-N2-[N-[(9H-fluoren-9-ylMethoxy)carbonyl]-L-valyl]-
FMOC-VAL-OSU
FMoc-Val-Cit-PAB
Methanol

FMoc-Val-Cit-PAB-PNP - Preparation solution concentration reference

 1mg5mg10mg
1 mM1.304 ml6.521 ml13.041 ml
5 mM0.261 ml1.304 ml2.608 ml
10 mM0.13 ml0.652 ml1.304 ml
5 mM0.026 ml0.13 ml0.261 ml
Last Update:2024-01-02 23:10:35

FMoc-Val-Cit-PAB-PNP - Reference Information

use FMoc-Val-Cit-PAB-PNP is an organic intermediate that can be used to prepare polypeptide couplings.
Preparation FMoc-Val-Cit-PAB-PNP can be prepared from L-valine and L-citrulline as raw materials through five steps The reaction is obtained.
biological activity Fmoc-Val-Cit-PAB-PNP is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
target Cleavable
Last Update:2024-04-10 22:29:15

FMoc-Val-Cit-PAB-PNP - Uses and synthesis methods

Preparation

FMoc-Val-Cit-PAB-PNP can be prepared from L-valine and L-citrulline through a five-step reaction.

Target

Cleavable

Last Update:2024-04-10 22:29:15
FMoc-Val-Cit-PAB-PNP
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CAS: 863971-53-3
Tel: +86-18821248368
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CAS: 863971-53-3
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CAS: 863971-53-3
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CAS: 863971-53-3
Tel: 18301782025
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View History
FMoc-Val-Cit-PAB-PNP
SGC 707
Cobaltous sulfate
依曲韦林杂质 11
176504-01-1
1-(4-环己基苄基)哌啶
REACTIVE RED 194
Cobalt(II) Sulfate Heptahydrate
Poly (oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy-, ether with oxybis[propanediol], octadecanoate
Polypropylene glycol 1000 dimethacrylate
Raw Materials for FMoc-Val-Cit-PAB-PNP
BIS(4-NITROPHENYL) CARBONATE
4-Nitrophenyl chloroformate
L-Ornithine, N5-(aMinocarbonyl)-N2-[N-[(9H-fluoren-9-ylMethoxy)carbonyl]-L-valyl]-
FMOC-VAL-OSU
FMoc-Val-Cit-PAB
Methanol
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