中文名 | Melanin Concentrating Hormone salmon |
英文名 | Melanin Concentrating Hormone salmon |
别名 | 黑素浓集素 黑色素聚集激素肽 鲑鱼黑色素聚集激素 黑色素聚集激酶素(MCH |
英文别名 | MCH (SALMON) MELANIN CONCENTRATING HORMONE Melanin Concentrating Hormone salmon MELANIN CONCENTRATING HORMONE, SALMON ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL H-ASP-THR-MET-ARG-CYS-MET-VAL-GLY-ARG-VAL-TYR-ARG-PRO-CYS-TRP-GLU-VAL-OH |
CAS | 87218-84-6 |
化学式 | C89H139N27O24S4 |
分子量 | 2099.5 |
密度 | 1.52±0.1 g/cm3(Predicted) |
存储条件 | −20°C |
外观 | 固体 |
MDL号 | MFCD00080194 |
体外研究 | An orphan G protein-coupled receptor (SLC-1/GPR24) has been identified as a receptor for MCH (MCHR1). MCHR2 has higher protein sequence homology to MCHR1 than any other G protein-coupled receptor. MCHR2 is specifically activated by nanomolar concentrations of MCH, binds to MCH with high affinity, and signals through Gq protein. |
体内研究 | Melanin Concentrating Hormone stimulates appetite. Continuous infusion of Melanin Concentrating Hormone into the ventricular system increases food intake for 7-8 days. Intracerebroventricular infusion of Melanin Concentrating Hormone (10 μg/day) causes a slight but significant increase in body weight in mice maintained on the regular diet. Chronic stimulation of the brain Melanin Concentrating Hormone system could cause obesity in mice. |
安全术语 | S22 - 切勿吸入粉尘。 S24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
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