Chorionic gonadotrophin chain β
儿茶素没食子酸酯(Catechin gallate)
CAS: 130405-40-2
化学式: C22H18O10
| 中文名 | 儿茶素没食子酸酯 |
| 英文名 | Catechin gallate |
| 别名 | 儿茶素没食子酸 儿茶素没食子酸酯 儿茶素没食子酯酸 儿茶素没食子酸酯CG (-)-没食子酸儿茶素酯 (-)-儿茶素没食子酸酯 (-)-儿茶素没食子酸酯, 来源于绿茶 (2S,3R)-2-(3,4-二羟苯基)-3,4-二氢-1(2H)-苯并-3,5,7-三醇3-(3,4,5-三羟基苯甲酸) |
| 英文别名 | Catechin gallate (-)-Catechin gallate(CG) (-)-Catechin 3-O-gallate) Choriogonadotropin subunit β Chorionic gonadotrophin chain β ANTI-CG antibody produced in mouse Catechin gallate CG (-)-Catechin gallate (-)-Catechin gallate ((-)-Catechin 3-gallate Anti-HCG β, C-Terminal antibody produced in rabbit |
| CAS | 130405-40-2 |
| 化学式 | C22H18O10 |
| 分子量 | 442.37 |
| InChIKey | LSHVYAFMTMFKBA-CTNGQTDRSA-N |
| 密度 | 1.80±0.1 g/cm3(Predicted) |
| 熔点 | 248-251 °C (decomp) |
| 沸点 | 861.7±65.0 °C(Predicted) |
| 溶解度 | DMSO (微溶) 、乙醇 (微溶) |
| 酸度系数 | 7.75±0.25(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 固体 |
| 颜色 | Pale Yellow to Light Red |
| 物化性质 | 白色粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于绿茶。 |
| MDL号 | MFCD00214258 |
| 体外研究 | (-)-Catechin gallate (CG) directly interacts with DNA oligomers and inhibits the activity of COX-1 and COX-2 enzymes, the gene expression of matrix metalloproteinase-9 in macrophage-differentiated HL-60 myeloid leukemia cells, the adipocyte uptake of glucose by the transporter, GLUT4, and the activities of various proteasomes, i.e., the multicatalytic proteases responsible for the degradation of most cellular proteins. The relative cytotoxicities of a 3-day exposure to (-)-Catechin gallate are determined for cancerous CAL27 and HSG cells, immortalized epithelioid S-G cells, and normal HGF-1 gingival fibroblasts. The concentration at which toxicity (P≤0.01) initially occur is 25 μM (-)-Catechin gallate for S-G cells, 50 μM (-)-Catechin gallate for CAL27 cells, 62.5 μM (-)-Catechin gallate for HSG cells and 75 μM (-)-Catechin gallate for HGF-1 fibroblasts. The calculated neutral red (NR 50 ) values for a 3-day exposure to (-)-Catechin gallate are 58 μM for S-G cells, 62 μM for CAL27 cells, 90 μM for HSG cells and 132 μM for HGF-1 fibroblasts. |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 S36 - 穿戴适当的防护服。 |
| WGK Germany | 3 |
| 海关编号 | 29329990 |
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Molecular nutrition & food research 63.17 (2019): 1801039.https://doi.org/10.1002/mnfr.201801039 18. Liu, Shuyuan, et al. "Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake." Food chemistry 234 (2017): 168-173.https://doi.org/10.1016/j.foodchem.2017. 19. Liu, Shuyuan, et al. "Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake." Food chemistry 234 (2017): 168-173.https://doi.org/10.1016/j.foodchem.2017. 20. Liu, Shuyuan, et al. "Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake." Food chemistry 234 (2017): 168-173.https://doi.org/10.1016/j.foodchem.2017. 21. [IF=7.514] Shuyuan Liu et al."Effect of steeping temperature on antioxidant and inhibitory activities of green tea extracts against α-amylase, α-glucosidase and intestinal glucose uptake."Food Chem. 2017 Nov;234:168 22. [IF=5.396] Jiachan Zhang et al."Understanding the role of extracts from sea buckthorn seed residues in anti-melanogenesis properties on B16F10 melanoma cells."Food Funct. 2018 Oct;9(10):5402-5416 23. [IF=3.659] Liu Shuyuan et al."In vitro α-glucosidase inhibitory activity of isolated fractions from water extract of Qingzhuan dark tea."Bmc Complem Altern M. 2016 Dec;16(1):1-8 24. [IF=3.06] Zeyi Ai et al."Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers."Molecules. 2019 Jan;24(6):1185 25. 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Chorionic gonadotrophin chain β - 简介
儿茶素没食子酸酯（Epicatechin gallate）是一种化合物，属于茶多酚类化合物。它是茶叶中的主要成分之一，尤其是绿茶中含量较高。
儿茶素没食子酸酯具有抗氧化、抗炎、抗菌和抗癌等多种生理活性。儿茶素没食子酸酯还具有抗糖尿病和降低胆固醇等作用。
制取儿茶素没食子酸酯一般采用提取和结晶方法。通过将茶叶浸泡在适当的溶剂中，如乙醇，来提取茶叶中的茶多酚类化合物。然后，通过过滤和浓缩过程将提取液中的杂质去除，获得所需的儿茶素没食子酸酯溶液。通过结晶过程将溶液中的儿茶素没食子酸酯结晶出来。
儿茶素没食子酸酯在一般情况下被认为是安全的。在使用过程中仍应注意适量饮用，避免过量摄入而引起不适。对于儿童、孕妇和哺乳期妇女，应遵医嘱使用。个别人群可能对儿茶素没食子酸酯过敏，在使用之前应先进行适度的皮肤敏感性测试。
儿茶素没食子酸酯具有抗氧化、抗炎、抗菌和抗癌等多种生理活性。儿茶素没食子酸酯还具有抗糖尿病和降低胆固醇等作用。
制取儿茶素没食子酸酯一般采用提取和结晶方法。通过将茶叶浸泡在适当的溶剂中，如乙醇，来提取茶叶中的茶多酚类化合物。然后，通过过滤和浓缩过程将提取液中的杂质去除，获得所需的儿茶素没食子酸酯溶液。通过结晶过程将溶液中的儿茶素没食子酸酯结晶出来。
儿茶素没食子酸酯在一般情况下被认为是安全的。在使用过程中仍应注意适量饮用，避免过量摄入而引起不适。对于儿童、孕妇和哺乳期妇女，应遵医嘱使用。个别人群可能对儿茶素没食子酸酯过敏，在使用之前应先进行适度的皮肤敏感性测试。
最后更新：2024-04-09 21:01:54
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产品名: 儿茶素没食子酸酯(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IC01501
产地: 北京
包装: 1ml/瓶
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库存: 现询
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提供多种规格现货供应
产品名: (-)-Catechin gallate 去供应商网站查看 询盘CAS: 130405-40-2
产地: 美国
包装: 1 mg;5 mg;10 mg;25 mg
规格: HY-N0356
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产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: 99.98%
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产品名: 儿茶素杂质6 ((-)-儿茶素没食子酸酯) 去供应商网站查看 询盘CAS: 130405-40-2
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
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产品描述: 43206C
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产品名: (-)-没食子酸儿茶素酯 去供应商网站查看 询盘CAS: 130405-40-2
产地: 上海
规格: C824145
价格: 5mg-998,10mg-1699,25mg-2500
库存: 现货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
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微信: 19863730987/17821173903
提供多种规格现货供应
产品名: 儿茶素没食子酸酯(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: IC01501
产地: 北京
包装: 1ml/瓶
规格: IC01501-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 产品覆盖：小分子化合物、分析对照品、染色试剂、生化试剂盒、细胞生物学、分子生物学、抗体、蛋白、多肽、ELISA试剂盒、微生物培养、化学合成、仪器耗材、CRO技术 更多
提供多种规格现货供应
产品名: (-)-Catechin gallate 去供应商网站查看 询盘CAS: 130405-40-2
产地: 美国
包装: 1 mg;5 mg;10 mg;25 mg
规格: HY-N0356
库存: 现货，货期：1-2天
电话: 021-38924433; 021-58955995
手机: 18019480960
电子邮件: sales@medchemexpress.cn
产品描述: 产品覆盖：8万多种抑制剂，11000+靶点蛋白，数百款试剂盒，200+生物活性化合物库，天然产物，抗体等. 纯度: 99.98%
现货供应
产品名: 儿茶素杂质6 ((-)-儿茶素没食子酸酯) 去供应商网站查看 询盘CAS: 130405-40-2
产地: 中国-STD
包装: 支
规格: 10mg，25mg，50mg，100mg
价格: 电询
库存: 现货
手机: 15671228036
电子邮件:
产品描述: 43206C
现货供应
产品名: (-)-没食子酸儿茶素酯 去供应商网站查看 询盘CAS: 130405-40-2
产地: 上海
规格: C824145
价格: 5mg-998,10mg-1699,25mg-2500
库存: 现货
电话: 13816333479/17821173903
手机: 13816333479/17821173903
电子邮件: wangrui@macklin.cn
QQ: 2881510266
微信: 19863730987/17821173903
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