中文名 | 木犀草苷 |
英文名 | Luteolin-7-glucoside |
别名 | 青兰苷 木犀草苷 朝蓟糖甙 木犀草苷(青兰苷 木犀草素-7-葡萄糖苷 木犀草苷(分析标准品) 木犀草素7-0葡萄糖苷 木樨草素-7-O-葡萄糖甙 木犀草素-7-O-葡萄糖甙 木犀草素-7-O-葡萄糖苷 藤黄菌素-7 -O-葡糖苷 木犀草素-7-O-葡萄糖苷,青兰苷 木犀草素7-O-Β-D-吡喃葡萄糖苷 木犀草素-7-O-D-吡喃葡萄糖苷, 来源于秦艽根茎 青兰苷,木犀草素-7-O-Β-D-葡萄糖苷,木犀草素-7-O-葡萄糖苷,木犀草素-7-葡萄糖苷,木犀素-7-0-葡萄糖苷,藤黄菌素-7 -O-葡糖苷,木犀草素-7-O-葡萄糖甙,木犀草素7-O-Β-D-吡喃葡萄糖苷 木犀草苷(青兰苷,木犀草素-7-O-Β-D-葡萄糖苷,木犀草素-7-O-葡萄糖苷,木犀草素-7-葡萄糖苷,木犀素-7-0-葡萄糖苷,藤黄菌素-7 -O-葡糖苷,木犀草素-7-O-葡萄糖甙,木犀草素7-O-Β-D-吡喃葡萄糖苷) |
英文别名 | CYNAROSIDE Cinaroside Cynaroside luteoloside Luteoloside Glucoluteolin 7-Glucoluteolin 7-Glucosylluteolin Luteolin-7-glucoside Luteolin 7-glucoside LUTEOLIN-7-GLUCOSIDE LUTEOLIN-7-O-GLUCOSIDE Luteolin 7-O-D-glucoside Luteolin 7-monoglucoside luteolin7-o-glucopyranoside Luteolin 7-O-glucopyranoside LUTEOLIN-7-O-GLUCOSIDE WITH HPLC 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl hexopyranoside 2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-hydroxy-4h-1-benzopyr 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-7-(beta-d-glucopyranosyloxy)-5-h 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-yl beta-D-glucopyranoside Furo[3,4-e]-1,3-benzodioxol-8(6H)-one, 6-(1,3-dioxolo[4,5-g]isoquinolin-5-yl)- 2-(3,4-Dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-5-hydroxy- 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(.beta.-D-glucopyranosyloxy)-5-hydroxy- 2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
CAS | 5373-11-5 |
EINECS | 226-365-8 |
化学式 | C21H20O11 |
分子量 | 448.38 |
InChI | InChI=1/C21H20O11/c22-7-16-18(27)19(28)20(29)21(32-16)30-9-4-12(25)17-13(26)6-14(31-15(17)5-9)8-1-2-10(23)11(24)3-8/h1-6,16,18-25,27-29H,7H2 |
InChIKey | PEFNSGRTCBGNAN-QNDFHXLGSA-N |
密度 | 1.713±0.06 g/cm3(Predicted) |
熔点 | 256~258℃ |
沸点 | 838.1±65.0 °C(Predicted) |
闪点 | 296.8°C |
蒸汽压 | 8.25E-30mmHg at 25°C |
溶解度 | DMSO (微溶) 、甲醇 (微溶) |
折射率 | 1.74 |
酸度系数 | 6.10±0.40(Predicted) |
存储条件 | Sealed in dry,2-8°C |
稳定性 | 吸湿性 |
外观 | 整洁 |
颜色 | Yellow to Very Dark Yellow |
物化性质 | 黄色结晶粉末,可溶于甲醇、乙醇、DMSO等有机溶剂,来源于菊花、地黄,锦灯笼、金银花,飞廉,莲子心 Nelumbo nucifera,问荆 Equisetum arvense.。 |
MDL号 | MFCD06799436 |
危险品标志 | Xi - 刺激性物品 |
安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
WGK Germany | 3 |
RTECS | DJ3009400 |
海关编号 | 29389090 |
参考资料 展开查看 | 1. 陆承云 张传博.1株曲霉属真菌(Aspergillus sp.)固体发酵对金银花及叶的活性成分影响[J].微生物学杂志 2018 38(04):48-55. 2. 郭静 王浩然 沈周媛 张彤 袁秀荣 丁越.3种竹叶抗氧化有效成分分析[J].中成药 2019 41(11):2688-2694. 3. 刘爽 杨健 查良平 赵玉洋 刘勇 袁媛 黄璐琦.5-氮杂胞苷影响LjFNS Ⅱ1.1和LjFNS Ⅱ2.1催化金银花木犀草素和木犀草苷合成机制的研究[J].中国中药杂志 2016 41(19):3597-3601. 4. 吕丹丹 何佳 宋文华 等. 8种乳酸菌发酵对凤丹花瓣中酚类物质及 其抗氧化活性的影响[J]. 食品与机械 2018 34(11):146-151. 5. 刘倩 张敏敏 李圣波 等. HPLC-DAD法测定西藏产区金银花花蕾及叶中化学成分含量[J]. 山东科学 2018 031(004):20-25. 6. 郑成凤 潘裕添 苑小宁 等. HPLC-UV-MS法对洋蓟中多酚类化合物的分析和鉴定[J]. 漳州师范学院学报(自然科学版) 2013(3):81-87. 7. 温子帅 刘露露 李新蕊 等. HPLC法同时测定不同产地荆芥中8种成分的含量[J]. 中药材 2019(1). 8. 孙婷婷 魏雅平 程红 等. HPLC法同时测定不同栽培区域滁菊中8种成分含量[J]. 安徽科技学院学报 2019 33(01):40-46. 9. 周送桂 何琚 王鲁. HPLC法同时测定金英黄归汤中芦丁 槲皮素和木犀草素的含量[J]. 中华中医药学刊 2016 034(012):2910-2912. 10. 王玲娜 刘红燕 张金 等. "一测多评法"与外标法测定金银花中8种活性成分含量[J]. 中国实验方剂学杂志 2014 20(20):57-61. 11. 王玲娜 陈燕文 赵振华 等. "华金6号"金银花新品种药材适宜采收期研究[J]. 四川农业大学学报 2016 v.34;No.128(01):100-104. 12. 苏征 王玲娜 张芳 等. 不同产地忍冬藤HPLC指纹图谱比较研究[J]. 时珍国医国药 2017(05):193-195. 13. 谭湘杰 于福来 黄梅 等. 不同初加工方式对裸花紫珠主要化学成分含量影响[J]. 热带农业科学 2018 v.38;No.251(07):36-42. 14. 师仁丽 翟龙飞 于文龙 等. 利用DAD-HPLC和LC-MS法检测金丝小枣中黄酮类化合物[J]. 食品科学 2016(16期):123-127. 15. 刘倩 康如龙 苏小建. 单一流动相同时测定绿原酸和木犀草苷的含量[J]. 食品研究与开发 2013 34(20):84-86. 16. 张启立, 夏鹏飞, 吴沂云,等. 大孔吸附树脂优选短筒兔耳草总黄酮的纯化工艺[J]. 中国医院药学杂志, 2016, 036(007):552-557. 17. 周霄楠, 韩超, 宋鹏琰,等. 木犀草素和槲皮素体外抗炎作用研究[J]. 动物医学进展, 2017, 38(010):56-61. 18. 王善善, 苑小宁, 杜鹏,等. 木犀草素在C(60)衍生物修饰电极上的电化学行为[J]. 广东化工, 2017, 44(005):18-19. 19. 姜泽群, 李沐涵, 马艳霞,等. 木犀草素通过上调microRNA-34a-5p诱导肺癌细胞株H460凋亡的研究[J]. 天然产物研究与开发, 2018, 030(002):169-175,324. 20. 邵圣娟. 花生壳中黄酮类化合物的提取纯化工艺研究[J]. 山西化工, 2016. 21. 张玉姗, 刘谢英, 姚新成,等. 高效液相色谱法同时测定茵栀黄颗粒中14个化学成分[J]. 药物分析杂志, 2019, 039(007):1229-1238. 22. 李冬梅, 夏日耀, 杜莲朵,等. 金银花不同部位营养成分分析[J]. 食品研究与开发, 2018(18):190-194. 23. 朱广平, 戴雨晨, 刘顺,等. 多指标综合评分法优选抗感胶囊提取工艺[J]. 中国中医药信息杂志, 2019, 026(003):77-81. 24. 谭湘杰, 于福来, 庞玉新,等. 海南裸花紫珠药材中7种成分含量分析[J]. 中国现代中药, 2018, 20(002):173-178. 25. 邹庆军, 汪涛, 郭巧生,等. 淹水胁迫对杭菊F3'H基因表达及其下游产物含量的影响[J]. 中国中药杂志, 2018. 26. 杨晓满, 张枫源, 向福,等. 金银花提取液通过改善肠道微生物和增强肠粘膜免疫促进宿主健康[J]. 基因组学与应用生物学, 2020, v.39(03):287-293. 27. 张芳, 孙希芳, 张永清,等. 金银花药材的HPLC指纹图谱及绿原酸,木犀草苷含量的同时测定. 28. 黄玉娟, 舒一崧, 孔静, et al. 基于特征图谱的金银花与山银花(灰毡毛忍冬)质量表征比较研究[J]. 环球中医药 2020年13卷4期, 600-610页, ISTIC CA, 2020. 29. 马云, 王尧尧, 王蕾,等. 忍冬花发育期间形态与13种活性成分含量变化[J]. 中药材, 2018, 041(007):1559-1565. 30. 阮飞,张宽朝,何孔泉,金青,王亚哲,蔡永萍,林毅,宋程,杨家平.昆仑雪菊活性成分的高效液相色谱测定方法改良及不同品系成分的测定[J].安徽农业大学学报,2016,43(04):646-650. 31. 冯晓燕, 房伟民, 陈发棣,等. 茶、药兼用菊新品系选育[J]. 中药材, 2017(2). 32. 李晓芳, 刘云宏, 马丽婷,等. 远红外辐射温度对金银花干燥特性及品质的影响[J]. 食品科学, 2017(15):81-88. 33. 梁从莲, 刘红燕, 崔媛,等. 金银花指纹图谱及其清除DPPH自由基的谱-效关系[J]. 中国实验方剂学杂志, 2015. 34. 黄梅, 于福来, 陈振夏,等. 土壤因子对裸花紫珠有效成分含量的影响研究[J]. 中国药房, 2018(1):2095-2099. 35. 王玲娜, 刘红燕, 李佳,等. 忍冬叶有效成分含量与气候因子的灰色关联分析[J]. 山东农业科学, 2014(11):57-60. 36. 朱姮, 于金倩, 刘倩,等. 基于RRLC-DAD-ESI-Q-TOF-MS技术的山东金银花多指标定量指纹图谱分析[J]. 中国实验方剂学杂志, 2017, 023(019):82-89. 37. 刘顺, 戴雨晨, 李存玉,等. 抗感胶囊的质量标准研究[J]. 中华中医药学刊, 2019(6):1310-1313. 38. 张静, 张建逵, 厉妲,等. 野菊花显微特征常数与化学成分相关性研究[J]. 时珍国医国药, 2015, 026(005):1257-1259. 39. 王玲娜,苏征,刘星劼,张芳,刘谦,张永清.金银花活性成分与生态因子相关性研究[J].中国实验方剂学杂志,2016,22(17):27-31. 40. 张慧, 李思雨, 冯宏玲,等. 基于效应成分指数的双黄连制剂质量控制研究[J]. 药学学报, 2019, 054(012):2149-2154. 41. 郭爽, 李庆, 何婉婉,等. 鸡冠花有效成分与药材粉末颜色的相关性[J]. 中国实验方剂学杂志, 2016, 022(024):64-69. 42. 唐君, 付强, 崔勐,等. 黄酮与溶菌酶相互作用的强度衰减-基质辅助激光解吸离子化-质谱研究[J]. 分析化学, 2016, 044(007):1071-1076. 43. 张敏敏, 刘代成, 王岱杰,等. SPME-GC/MS联合HSDE-HPLC-DAD分析表征金银花新品种中的主要化学成分[J]. 天然产物研究与开发, 2016, 028(009):1390-1396,1413. 44. 陈智. 金银花和黄芩不同煎煮方式化学成分变化及抗病毒作用比较[J]. 中华中医药杂志, 2019, v.34(10):129-133. 45. 王伟,何平,江小明.木犀草素及其黄酮苷的抗炎、抗氧化作用[J].食品科学,2020,41(17):208-215. 46. 邓亚雷,王飞飞,曲丽萍.酸浆中木犀草苷提取工艺优化[J].食品安全质量检测学报,2021,12(04):1332-1337. 47. 杨金宏,彭云武,陈正余,孔卫青.安康地区桑叶主要功能物质的含量与抗氧化活性[J].贵州农业科学,2020,48(09):33-36. 48. 王文琪,李媛媛,王双,朱彦军,孙梦佳,蔡馥洁,孙晓慧,柳晴,周洪雷.败酱草总黄酮部位体外抗病毒活性成分研究[J].山东科学,2020,33(05):43-50. 49. 王宇卿,李淑娇,庄果.基于HPLC-Q-TOF/MS法的鬼针草血清药物化学探究[J].中成药,2020,42(11):3074-3078. 50. 李丽丽,李月,卢恒,王晓.基于液相色谱-质谱法的不同花期金银花代谢组学分析[J].分析测试学报,2020,39(12):1501-1507. 51. Liu, Chanmin, et al. "Flavonoid-rich extract of Paulownia fortunei flowers attenuates diet-induced hyperlipidemia, hepatic steatosis and insulin resistance in obesity mice by AMPK pathway." Nutrients 9.9 (2017): 959.https://doi.org/10.3390/nu9090959 52. Ma, Ning-Hui, et al. "Antioxidant and compositional HPLC analysis of three common bamboo leaves." Molecules 25.2 (2020): 409.10.4314/ajtcam.v13i1.14 53. Xue, Gen, et al. "Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA." Journal of Analytical Methods in Chemistry 2021 (2021).https://doi.org/10.11 54. [IF=4.411] Ying Zhang et al."Compounds Identification in Semen Cuscutae by Ultra-High-Performance Liquid Chromatography (UPLCs) Coupled to Electrospray Ionization Mass Spectrometry."Molecules. 2018 May;23(5):1199 55. [IF=4.171] Chanmin Liu et al."Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway."Nutrients. 2017 Sep;9(9):959 56. [IF=1.902] Yining Zhao et al."Simultaneous quantitation of 23 bioactive compounds in Tanreqing capsule by high-performance liquid chromatography electrospray ionization tandem mass spectrometry."Biomed Chromatogr. 2019 Jul;33(7):e4531 57. [IF=11.413] Sifan Luo et al."Rapid identification and isolation of neuraminidase inhibitors from mockstrawberry (Duchesnea indica Andr.) based on ligand fishing combined with HR-ESI-Q-TOF-MS."Acta Pharm Sin B. 2020 Oct;10:1846 58. [IF=6.312] Mengyang Hou et al."Ultrasound-Assisted Extraction of Total Flavonoids from Pteris cretica L.: Process Optimization, HPLC Analysis, and Evaluation of Antioxidant Activity."Antioxidants-Basel. 2019 Oct;8(10):425 59. [IF=5.645] Zhang-Zhen Bai et al."Comparative investigation on metabolites and biological activities of Paeonia ostii stamens from different geographical regions of China."Ind Crop Prod. 2021 Nov;172:114038 60. [IF=5.645] Qiang Zhang et al."A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical composition and antioxidant activity."Ind Crop Prod. 2020 Oct; 61. [IF=5.076] Zhang Zepeng et al."Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway."Oxid Med Cell Longev. 2020;2020:3426925 62. [IF=4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447 63. [IF=4.759] Fengli Chen et al."Magnetically stabilized bed packed with synthesized magnetic silicone loaded with ionic liquid particles for efficient enrichment of flavonoids from tree peony petals."J Chromatogr A. 2020 Feb;1613:460671 64. [IF=4.411] Ning-Hui Ma et al."Antioxidant and Compositional HPLC Analysis of Three Common Bamboo Leaves."Molecules. 2020 Jan;25(2):409 65. [IF=4.35] Chengcheng Zhang et al."Chemical Characterization and Antioxidant Properties of Ethanolic Extract and Its Fractions from Sweet Potato (Ipomoea batatas L.) Leaves."Foods. 2020 Jan;9(1):15 66. [IF=3.645] Jie Lu et al."Identification and determination of chemical constituents from Yinchen Qingjin granules by ultra high-performance liquid chromatography coupled with linear ion trap-Orbitrap mass spectrometry."J Sep Sci. 2021 Apr;44(7):1324-1344 67. [IF=2.193] Xue Gen et al."Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA."J Anal Methods Chem. 2021;2021:9991363 68. [IF=1.902] Hongyan Liu et al."Spectrum–effect relationship study between HPLC fingerprints and antioxidant of honeysuckle extract."Biomed Chromatogr. 2019 Oct;33(10):e4583 69. [IF=1.813] Zhang Ying et al."Comparative Studies on Chemical Contents and Effect in Kidney-Yang Deficiency Rats of Salt-Processed Product and Wine-Processed Product of Cuscutae Semen."Evid-Based Compl Alt. 2019;2019:2049497 70. [IF=1.552] Fang Mingyue et al."Qualitative and Quantitative Analysis of 24 Components in Jinlianhua Decoction by UPLC–MS/MS."Chromatographia. 2019 Dec;82(12):1801-1825 71. [IF=2.863] Xiaokang Liu et al."Spectrum–effect relationship between ultra-high-performance liquid chromatography fingerprints and antioxidant activities of Lophatherum gracile Brongn."Food Science & Nutrition. 2022 Feb 22 72. [IF=3.935] Junmao Li et al."Comprehensive chemical profiling of the flowers of Citrus aurantium L. var. amara Engl. and uncovering the active ingredients of lipid lowering."J Pharmaceut Biomed. 2022 Mar;211:114621 73. [IF=6.576] Guowei Man et al."Profiling Phenolic Composition in Pomegranate Peel From Nine Selected Cultivars Using UHPLC-QTOF-MS and UPLC-QQQ-MS."Front Nutr. 2021; 8: 807447 74. [IF=2.506] Liu Meiqi et al."Assessing the Quality of Calyx of Physalis alkekengi L. var. franchetii Based on Quantitative Analysis of Q-Marker Combined with Chemometrics and Machine Learning Algorithms."J Chem-Ny. 2021;2021:8502929 75. [IF=4.411] Junfeng Hao et al."Comparative Analysis of Major Flavonoids among Parts of Lactuca indica during Different Growth Periods."Molecules. 2021 Jan;26(24):7445 76. [IF=4.36] Zhiyong Zhang et al."On-line screening of natural antioxidants and the antioxidant activity prediction for the extracts from flowers of Chrysanthemum morifolium ramat."JOURNAL OF ETHNOPHARMACOLOGY. 2022 Aug;294:115336 77. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177 78. [IF=7.514] Jie Meng et al."Conduction of a chemical structure-guided metabolic phenotype analysis method targeting phenylpropane pathway via LC-MS: Ginkgo biloba and soybean as examples."FOOD CHEMISTRY. 2022 Oct;390:133155 79. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426 |
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