红景天素(草质素苷)
红景天素(Rhodiosin; Herbacetin-7-O-glucorhamnoside)
CAS: 86831-54-1
化学式: C27H30O16
| 中文名 | 红景天素 |
| 英文名 | Rhodiosin Herbacetin-7-O-glucorhamnoside |
| 别名 | 鼠李糖苷 红景天素 红景天素对照品 红景天素标准品 红景天素(草质素苷) 草质素-7-O-(3′′-Β-D-葡萄糖基)-Α-L-鼠李糖苷 |
| 英文别名 | Rhodiosin RHODIOSIN HERBACETIN-7-O-GLUCORHAMNOSIDE Rhodiosin Herbacetin-7-O-glucorhamnoside herbacetin 7-O-(3''-O-β-D-glucopyranosyl-α-L-rhamnopyranoside) 7-[(3-O-β-D-Glucopyranosyl-α-L-rhamnopyranosyl)oxy]-3,4',5,8-tetrahydroxyflavone 7-[3-O-(β-D-Glucopyranosyl)-α-L-rhamnopyranosyloxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 7-[(6-deoxy-3-O-β-D-glucopyranosyl-α-L-mannopyranosyl)oxy]-3,5,8-trihydroxy-2-(4-hydroxyphenyl)- |
| CAS | 86831-54-1 |
| 化学式 | C27H30O16 |
| 分子量 | 610.52 |
| 密度 | 1.82±0.1 g/cm3(Predicted) |
| 熔点 | 195-199 °C |
| 沸点 | 994.3±65.0 °C(Predicted) |
| 溶解度 | 可溶于甲醇、乙醇、DMSO等有机溶剂 |
| 酸度系数 | 6.67±0.40(Predicted) |
| 存储条件 | 2-8°C |
| 外观 | 无色针状结晶 |
| 物化性质 | 白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于红景天。 |
| MDL号 | MFCD00238673 |
| 参考资料 展开查看 | 1. 赵亮 齐特 葛贝康 等. UPLC-MS/MS法测定红景天提取物中6种活性成分的含量[J]. 国际药学研究杂志 2016 43(005):975-979. 2. Nan, Xingmei, et al. "Bioactive fraction of Rhodiola algida against chronic hypoxia-induced pulmonary arterial hypertension and its anti-proliferation mechanism in rats." Journal of ethnopharmacology 216 (2018): 175-183.https://doi.org/10.1016/j.jep.2018.0 3. Fei Han, Yanting Li, Li Ma, Tianfeng Liu, Yawen Wu, Rui Xu, Aihua Song, Ran Yin,A rapid and sensitive UHPLC-FT-ICR MS/MS method for identification of chemical constituents in Rhodiola crenulata extract, rat plasma and rat brain after oral administration, 4. Li, Yanting, et al. "Characterization of global metabolic profile of Rhodiola crenulata after oral administration in rat plasma, urine, bile and feces based on UHPLC-FT-ICR MS." Journal of pharmaceutical and biomedical analysis 149 (2018): 318-328.https:// 5. Han, Fei, et al. "Characterization of chemical constituents in Rhodiola Crenulate by high‐performance liquid chromatography coupled with Fourier‐transform ion cyclotron resonance mass spectrometer (HPLC‐FT‐ICR MS)." Journal of Mass Spectrometry 51.5 (2016) 6. Fei Han, Yanting Li, Li Ma, Tianfeng Liu, Yawen Wu, Rui Xu, Aihua Song, Ran Yin,A rapid and sensitive UHPLC-FT-ICR MS/MS method for identification of chemical constituents in Rhodiola crenulata extract, rat plasma and rat brain after oral administration, 7. [IF=6.057] Fei Han et al."A rapid and sensitive UHPLC-FT-ICR MS/MS method for identification of chemical constituents in Rhodiola crenulata extract, rat plasma and rat brain after oral administration."Talanta. 2016 Nov;160:183 8. [IF=3.935] Yanting Li et al."Characterization of global metabolic profile of Rhodiola crenulata after oral administration in rat plasma, urine, bile and feces based on UHPLC-FT-ICR MS."J Pharmaceut Biomed. 2018 Feb;149:318 9. [IF=3.69] Xingmei Nan et al."Bioactive fraction of Rhodiola algida against chronic hypoxia-induced pulmonary arterial hypertension and its anti-proliferation mechanism in rats."J Ethnopharmacol. 2018 Apr;216:175 10. [IF=1.982] Fei Han et al."Characterization of chemical constituents in Rhodiola Crenulate by high-performance liquid chromatography coupled with Fourier-transform ion cyclotron resonance mass spectrometer (HPLC-FT-ICR MS)."J Mass Spectrom. 2016 May;51(5):363-368 11. [IF=16.806] Shujing Zhang et al.Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy.Advanced Science.2021 Nov 10 12. [IF=6.543] Liu Yilong et al."Two Myricetin-Derived Flavonols from Morella rubra Leaves as Potent α-Glucosidase Inhibitors and Structure-Activity Relationship Study by Computational Chemistry."Oxidative Medicine and Cellular Longevity. 2022;2022:9012943 |
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